Titre :

Chicory roots for prebiotics and appetite regulation: a pilot study in mice.

Auteur(s) :

Foure, Marion [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
DUGARDIN, Camille [Auteur]
BioEcoAgro - UMR transfrontalière INRAe - UMRT1158
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Foligne, Benoit [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
HANCE, PHILIPPE [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Cadalen, Thierry [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Delcourt, Abigael [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Taminiau, Bernard [Auteur]
Université de Liège
Daube, George [Auteur]
Université de Liège
Ravallec, Rozenn [Auteur]
BioEcoAgro - UMR-T 1158
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Cudennec, Benoit [Auteur]
BioEcoAgro - UMR-T 1158
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Hilbert, Jean-Louis [Auteur]
BioEcoAgro - UMR-T 1158
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Lucau-Danila, Anca [Auteur]
Institut Charles Viollette (ICV) - EA 7394 [ICV]

Titre de la revue :

Journal of Agricultural and Food Chemistry

Nom court de la revue :

J. Agric. Food Chem.

Numéro :

66

Pagination :

6439–6449

Date de publication :

2018-06-27

ISSN :

1520-5118

Mot(s)-clé(s) :

Cichorium intybus
satiety hormones
metagenetics
metabolomics
prebiotics

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

The objectives of this work are to address the prebiotic effects of chicory (Cichorium intybus) together with its possible role in appetite control. We compared nine chicory genotypes in order to determine if variations ...
Lire la suite >The objectives of this work are to address the prebiotic effects of chicory (Cichorium intybus) together with its possible role in appetite control. We compared nine chicory genotypes in order to determine if variations in the content of metabolites in the roasted roots would lead to modifications in release of satiety hormones and in composition of gut microbiota. To this aim, a 5-week dietary-intervention study was achieved using mice fed with distinct chicory-based preparations. A 16S rRNA gene-based metagenetic analysis of fecal microbiota was performed. In vitro gastrointestinal digestions were performed in order to study the effect of chicory intestinal digests on gut hormone regulation in enteroendocrine cells. Firmicutes/Bacteroidetes ratio and gut bacterial groups, such as Alloprevotella, Blautia, Alistipes, and Oscillibacter, were found to be modulated by chicory. On the other hand, CCK and GLP-1 satiety hormones were demonstrated to be significantly increased by chicory in vitro.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

Inserm
Université de Lille
CHU Lille
INRA
ISA
Univ. Artois
Univ. Littoral Côte d’Opale

Collections :

• BioEcoAgro - UMR-T 1158
• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Équipe(s) de recherche :

Inflammatory digestive disease : pathophysiology and therapeutic targets developement

Date de dépôt :

2019-03-01T15:24:50Z
2024-02-12T14:42:53Z