Intercalation of Ciprofloxacin in Naturally ...
Type de document :
Article dans une revue scientifique
DOI :
URL permanente :
Titre :
Intercalation of Ciprofloxacin in Naturally Occurring Smectite from Bana: Potentiality as Drug Delivery System and Antimicrobial Effects on Escherichia coli and Staphylococcus aureus
Auteur(s) :
Memenfo, Carine Feudjio [Auteur]
Tabary, Nicolas [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Mbey, Jean Aimé [Auteur]
Degoutin, Stéphanie [Auteur]
Cazaux, Frédéric [Auteur]
Bacquet, maryse [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Maton, Mickaël [Auteur]
Martel, Bernard [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Njopwouo, Daniel [Auteur]
Tabary, Nicolas [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Mbey, Jean Aimé [Auteur]
Degoutin, Stéphanie [Auteur]
Cazaux, Frédéric [Auteur]
Bacquet, maryse [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Maton, Mickaël [Auteur]
Martel, Bernard [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Njopwouo, Daniel [Auteur]
Titre de la revue :
Journal of Materials Science and Chemical Engineering
Nom court de la revue :
MSCE
Numéro :
09
Pagination :
21-40
Éditeur :
Scientific Research Publishing, Inc.
Date de publication :
2021
Résumé en anglais : [en]
Ciprofloxacin (CFX) was loaded on Bana clay (Cameroon) and CFX loadedclays
have been evaluated as drug delivery system. Raw clays and CFX loaded
compounds have been characterized by some physico-chemicals methods. In
vitro ...
Lire la suite >Ciprofloxacin (CFX) was loaded on Bana clay (Cameroon) and CFX loadedclays have been evaluated as drug delivery system. Raw clays and CFX loaded compounds have been characterized by some physico-chemicals methods. In vitro release studies have been done in gastric and phosphate buffer experimental mediums; bacteriological studies have been made up on Escherichia coli and Staphylococcus aureus. X-ray diffractometry patterns of loaded compounds show a basal spacing increasing due to CFX intercalation. On Fourier-Transformed Infrared spectrometry spectra, appearance of CFX characteristic bands and shifting of certain bands already presents on clay confirmed CFX intercalation. After 96 h of CFX released from release mediums, prolonged and continue profiles have been observed. Diffusion tests displayed an inhibition radius of ~2 cm on gelose seeded with Escherichia coli and Staphylococcus aureus due to CFX. The overall results show a modified release of ciprofloxacin with an effective antibacterial activity, giving the way for a new ciprofloxacin drug delivery system using Bana clay as carrier.Lire moins >
Lire la suite >Ciprofloxacin (CFX) was loaded on Bana clay (Cameroon) and CFX loadedclays have been evaluated as drug delivery system. Raw clays and CFX loaded compounds have been characterized by some physico-chemicals methods. In vitro release studies have been done in gastric and phosphate buffer experimental mediums; bacteriological studies have been made up on Escherichia coli and Staphylococcus aureus. X-ray diffractometry patterns of loaded compounds show a basal spacing increasing due to CFX intercalation. On Fourier-Transformed Infrared spectrometry spectra, appearance of CFX characteristic bands and shifting of certain bands already presents on clay confirmed CFX intercalation. After 96 h of CFX released from release mediums, prolonged and continue profiles have been observed. Diffusion tests displayed an inhibition radius of ~2 cm on gelose seeded with Escherichia coli and Staphylococcus aureus due to CFX. The overall results show a modified release of ciprofloxacin with an effective antibacterial activity, giving the way for a new ciprofloxacin drug delivery system using Bana clay as carrier.Lire moins >
Langue :
Anglais
Comité de lecture :
Oui
Audience :
Non spécifiée
Établissement(s) :
Université de Lille
CNRS
INRA
ENSCL
CNRS
INRA
ENSCL
Collections :
Équipe(s) de recherche :
Ingénierie des Systèmes Polymères
Date de dépôt :
2021-09-02T13:29:32Z