New microfluidic designs for high-throughput ...
Document type :
Communication dans un congrès avec actes
Title :
New microfluidic designs for high-throughput analysis of angiogenesis, blood vessel permeability and endothelial activation
Author(s) :
Delannoy, E. [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Treizebre, Anthony [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Bio-Micro-Electro-Mechanical Systems - IEMN [BIOMEMS - IEMN]
SONCIN, Fabrice [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Treizebre, Anthony [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Bio-Micro-Electro-Mechanical Systems - IEMN [BIOMEMS - IEMN]
SONCIN, Fabrice [Auteur]
Conference title :
24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020
City :
Online
Country :
Etats-Unis d'Amérique
Start date of the conference :
2020-10-04
Book title :
Proceedings of the 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020
Journal title :
Proceedings of the 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020
HAL domain(s) :
Sciences de l'ingénieur [physics]
English abstract : [en]
Angiogenesis is the process by which new blood vessels arise from existing ones. Angiogenesis is involved in human cancers; new blood vessels favor tumor development by bringing oxygen and nutrients to the developing mass. ...
Show more >Angiogenesis is the process by which new blood vessels arise from existing ones. Angiogenesis is involved in human cancers; new blood vessels favor tumor development by bringing oxygen and nutrients to the developing mass. We designed angiogenesis-on-chip devices using a viscosity finger patterning technique for creating established blood vessels in hydrogels on which endothelial integrity and permeability could be assessed, and from which sprouting angiogenesis may be induced. These BioMEMS are designed in multiwell plate format to be used for high throughput drug screening.Show less >
Show more >Angiogenesis is the process by which new blood vessels arise from existing ones. Angiogenesis is involved in human cancers; new blood vessels favor tumor development by bringing oxygen and nutrients to the developing mass. We designed angiogenesis-on-chip devices using a viscosity finger patterning technique for creating established blood vessels in hydrogels on which endothelial integrity and permeability could be assessed, and from which sprouting angiogenesis may be induced. These BioMEMS are designed in multiwell plate format to be used for high throughput drug screening.Show less >
Language :
Anglais
Peer reviewed article :
Oui
Audience :
Internationale
Popular science :
Non
Comment :
oral
Source :