Title :

Elevated alveolar nitric oxide is linked to poor aerobic capacity and chronotropic incompetence in liver transplant candidates

Author(s) :

Hulo, Sebastien [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Edme, Jean-Louis [Auteur]
IMPact de l’Environnement Chimique sur la Santé humaine (IMPECS) - EA 4483
Inamo, Jocelyn [Auteur]
Centre Hospitalier Universitaire de Martinique [Fort-de-France, Martinique] [CHU de Martinique]
Van Bulck, Richard [Auteur]
Service d'explorations fonctionnelles respiratoires [Lille]
Dharancy, Sebastien [Auteur]
Hôpital Claude Huriez [Lille]
Neviere, Remi [Auteur]
Centre Hospitalier Universitaire de Martinique [Fort-de-France, Martinique] [CHU de Martinique]

Journal title :

Journal of breath research

Abbreviated title :

J Breath Res

Volume number :

12

Publisher :

IOPScience

Publication date :

2018-08-06

ISSN :

1752-7163

English keyword(s) :

liver transplantation
alveolar nitric oxide
chronotropic incompetence
aerobic capacity (VO(2)max)

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Increased nitric oxide is involved in abnormal hemodynamic parameters and respiratory function of cirrhotic patients. We aimed to quantify partitioning exhaled nitric oxide measurements in exhaled air in liver transplantation ...
Show more >Increased nitric oxide is involved in abnormal hemodynamic parameters and respiratory function of cirrhotic patients. We aimed to quantify partitioning exhaled nitric oxide measurements in exhaled air in liver transplantation (LT) candidates and evaluate their relationships with chronotropic incompetence and aerobic capacity. We compared exhaled nitric oxide (NO) measurements, heart rate response and peak oxygen uptake during incremental exercise in liver transplantation candidates to those of controls. As opposed to healthy control subjects, LT candidates displayed elevated alveolar NO, blunted chronotropic response and reduced V'O22-1-122 Increasing alveolar NO could be a specific pathophysiological condition limiting aerobic capacity in LT candidates.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Inserm
Institut Pasteur de Lille
Université de Lille

Collections :

• IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Submission date :

2022-02-02T10:23:42Z
2024-02-15T09:34:40Z