Title :

Does exposure to inflammatory particles modify the pattern of anion in exhaled breath condensate?

Author(s) :

Sauvain, Jean-Jacques [Auteur]
Edme, Jean-Louis [Auteur]
Wild, Pascal [Auteur]
Suarez, Guillaume [Auteur]
De Paula Alvez Bezerra, Olivia Maria [Auteur]
Talvani, Andre [Auteur]
Algranti, Eduardo [Auteur]
Carneiro, Ana Paula Scalio [Auteur]
Chérot-Kornobis, Nathalie [Auteur]
Sobaszek, Annie [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Hulo, Sebastien [Auteur]

Journal title :

Journal of breath research

Abbreviated title :

J Breath Res

Publication date :

2019-11-29

ISSN :

1752-7163

Keyword(s) :

quartz
small chain fatty acids
exhaled breath condensate
ion chromatography
metabolism
soapstone

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Exposure to environmental and occupational particulate matter (PM) induces health effects on the cardio-pulmonary system. In addition, associations between exposure to PM and metabolic syndromes like diabetes mellitus or ...
Show more >Exposure to environmental and occupational particulate matter (PM) induces health effects on the cardio-pulmonary system. In addition, associations between exposure to PM and metabolic syndromes like diabetes mellitus or obesity are now emerging in the literature. Collection of exhaled breath condensate (EBC) is an appealing non-invasive technique to sample pulmonary fluids. This hypothesis-generating study aims to (1) validate an ion chromatography method allowing the robust determination of different metabolism-related molecules (lactate, formate, acetate, propionate, butyrate, pyruvate, nitrite, nitrate) in EBC; (2) apply this method to EBC samples collected from workers exposed to quartz (a known inflammatory particle), to soapstone (a less inflammatory particle than quartz), as well as to controls. A multi-compound standard solution was used to determine the linearity range, detection limit, repeatability and bias from spiked EBC. The biological samples were injected without further treatment into an ion chromatograph with a conductivity detector. RTube®Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Institut Pasteur de Lille
Université de Lille

Collections :

• IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483

Submission date :

2022-02-02T10:24:25Z