Title :

Molecular Epidemiology of Blastocystis sp. in Various Animal Groups from Two French Zoos and Evaluation of Potential Zoonotic Risk

Author(s) :

Cian, Amandine [Auteur]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
El Safadi, Dima [Auteur]
University of Tripoli - University Al Fateh
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Osman, Marwan [Auteur]
University of Tripoli - University Al Fateh
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Moriniere, Romain [Auteur]
Gantois, Nausicaa [Auteur]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Benamrouz-Vanneste, Sadia [Auteur]
Université catholique de Lille [UCL]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Delgado-Viscogliosi, Pilar [Auteur]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Guyot, Karine [Auteur]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Li, Luen-Luen [Auteur]
Université du Littoral Côte d'Opale [ULCO]
Laboratoire d’Océanologie et de Géosciences (LOG) - UMR 8187 [LOG]
Monchy, Sébastien [Auteur]
Université du Littoral Côte d'Opale [ULCO]
Laboratoire d’Océanologie et de Géosciences (LOG) - UMR 8187 [LOG]
Noël, Christophe [Auteur]
Poirier, Philippe [Auteur]
Laboratoire Microorganismes : Génome et Environnement [LMGE]
Nourrisson, Céline [Auteur]
Laboratoire Microorganismes : Génome et Environnement [LMGE]
Wawrzyniak, Ivan [Auteur]
Laboratoire Microorganismes : Génome et Environnement [LMGE]
Delbac, Frédéric [Auteur]
Laboratoire Microorganismes : Génome et Environnement [LMGE]
Bosc, Stéphanie [Auteur]
Chabé, Magali [Auteur]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Petit, Thierry [Auteur]
Zoo de la Palmyre
Certad, Gabriela [Auteur]
Université catholique de Lille - Faculté de médecine et de maïeutique [UCL FMM]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Viscogliosi, Eric [Auteur correspondant]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]

Journal title :

PLOS ONE

Pages :

1-29 / e0169659

Publisher :

Public Library of Science

Publication date :

2017-01-06

ISSN :

1932-6203

English keyword(s) :

Birds
Biastocystis
Parasitic diseases
Zoonoses
Sequence databases
Insects
Lemurs
Tamarins

HAL domain(s) :

Planète et Univers [physics]/Sciences de la Terre/Océanographie

English abstract : [en]

Blastocystis sp. is a common intestinal parasite infecting humans and a wide range of animals worldwide. It exhibits an extensive genetic diversity and 17 subtypes (STs) have thus far been identified in mammalian and avian ...
Show more >Blastocystis sp. is a common intestinal parasite infecting humans and a wide range of animals worldwide. It exhibits an extensive genetic diversity and 17 subtypes (STs) have thus far been identified in mammalian and avian hosts. Since several STs are common to humans and animals, it was proposed that a proportion of human infections may result from zoonotic transmission. However, the contribution of each animal source to human infection remains to be clarified. Therefore, the aim of this study was to expand our knowledge of the epidemiology and host specificity of this parasite by performing the largest epidemiological survey ever conducted in animal groups in terms of numbers of species screened. A total of 307 stool samples from 161 mammalian and non-mammalian species in two French zoos were screened by real-time PCR for the presence of Blastocystis sp. Overall, 32. 2% of the animal samples and 37. 9% of the species tested were shown to be infected with the parasite. A total of 111 animal Blastocystis sp. isolates were subtyped, and 11 of the 17 mammalian and avian STs as well as additional STs previously identified in reptiles and insects were found with a varying prevalence according to animal groups. These data were combined with those obtained from previous surveys to evaluate the potential risk of zoonotic transmission of Blastocystis sp. through the comparison of ST distribution between human and animal hosts. This suggests that non-human primates, artiodactyls and birds may serve as reservoirs for human infection, especially in animal handlers. In contrast, other mammals such as carnivores, and non-mammalian groups including reptiles and insects, do not seem to represent significant sources of Blastocystis sp. infection in humans. In further studies, more intensive sampling and screening of potential new animal hosts will reinforce these statements and expand our understanding of the circulation of Blastocystis sp. in animal and human populations.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Collections :

• Laboratoire d'Océanologie et de Géosciences (LOG) - UMR 8187

Source :

Harvested from HAL