A Metabolic Perspective on Reward Abnormalities ...
Type de document :
Article dans une revue scientifique: Article de synthèse/Review paper
PMID :
URL permanente :
Titre :
A Metabolic Perspective on Reward Abnormalities in Anorexia Nervosa.
Auteur(s) :
Duriez, Philibert [Auteur]
Institut de psychiatrie et neurosciences de Paris [IPNP - U1266 Inserm]
Ramoz, Nicolas [Auteur]
Institut de psychiatrie et neurosciences de Paris [IPNP - U1266 Inserm - Paris Descartes]
Gorwood, Philip [Auteur]
Institut National de la Santé et de la Recherche Médicale [INSERM]
Viltart, Odile [Auteur]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193 [SCALab]
Institut de psychiatrie et neurosciences de Paris [IPNP - U1266 Inserm - Paris Descartes]
Tolle, Virginie [Auteur]
Institut de psychiatrie et neurosciences de Paris [IPNP - U1266 Inserm]
Institut de psychiatrie et neurosciences de Paris [IPNP - U1266 Inserm]
Ramoz, Nicolas [Auteur]
Institut de psychiatrie et neurosciences de Paris [IPNP - U1266 Inserm - Paris Descartes]
Gorwood, Philip [Auteur]
Institut National de la Santé et de la Recherche Médicale [INSERM]
Viltart, Odile [Auteur]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193 [SCALab]
Institut de psychiatrie et neurosciences de Paris [IPNP - U1266 Inserm - Paris Descartes]
Tolle, Virginie [Auteur]
Institut de psychiatrie et neurosciences de Paris [IPNP - U1266 Inserm]
Titre de la revue :
Trends in endocrinology and metabolism: TEM
Nom court de la revue :
Trends Endocrinol Metab
Numéro :
30
Pagination :
915-928
Date de publication :
2019-12
ISSN :
1879-3061
Mot(s)-clé(s) en anglais :
Anorexia Nervosa
Genome-Wide Association Study
Humans
anorexia nervosa
human genetics
metabolic factors
reward abnormalities
Genome-Wide Association Study
Humans
anorexia nervosa
human genetics
metabolic factors
reward abnormalities
Discipline(s) HAL :
Sciences cognitives
Résumé en anglais : [en]
Anorexia nervosa (AN) is the psychiatric disorder with the highest mortality rate; however, the mechanisms responsible for its pathogenesis remain largely unknown. Large-scale genome-wide association studies (GWAS) have ...
Lire la suite >Anorexia nervosa (AN) is the psychiatric disorder with the highest mortality rate; however, the mechanisms responsible for its pathogenesis remain largely unknown. Large-scale genome-wide association studies (GWAS) have identified genetic loci associated with metabolic features in AN. Metabolic alterations that occur in AN have been mostly considered as consequences of the chronic undernutrition state but until recently have not been linked to the etiology of the disorder. We review the molecular basis of AN based on human genetics, with an emphasis on the molecular components controlling energy homeostasis, highlight the main metabolic and endocrine alterations occurring in AN, and decipher the possible connection between metabolic factors and abnormalities of reward processes that are central in AN.Lire moins >
Lire la suite >Anorexia nervosa (AN) is the psychiatric disorder with the highest mortality rate; however, the mechanisms responsible for its pathogenesis remain largely unknown. Large-scale genome-wide association studies (GWAS) have identified genetic loci associated with metabolic features in AN. Metabolic alterations that occur in AN have been mostly considered as consequences of the chronic undernutrition state but until recently have not been linked to the etiology of the disorder. We review the molecular basis of AN based on human genetics, with an emphasis on the molecular components controlling energy homeostasis, highlight the main metabolic and endocrine alterations occurring in AN, and decipher the possible connection between metabolic factors and abnormalities of reward processes that are central in AN.Lire moins >
Langue :
Anglais
Comité de lecture :
Oui
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
CNRS
CHU Lille
CNRS
CHU Lille
Date de dépôt :
2022-05-04T12:38:57Z
2022-05-11T09:51:10Z
2022-05-11T09:51:10Z
Fichiers
- Duriez et al TEMS 2019.pdf
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