Analysis of Phthalates and Alternative ...
Document type :
Article dans une revue scientifique: Article original
DOI :
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Title :
Analysis of Phthalates and Alternative Plasticizers in Gloves by Gas Chromatography-Mass Spectrometry and Liquid Chromatography-UV Detection: A Comparative Study.
Author(s) :
Poitou, Kelly [Auteur]
Université de Rouen Normandie [UNIROUEN]
Rogez-Florent, Tiphaine [Auteur]
Université de Rouen Normandie [UNIROUEN]
Lecoeur, Marie [Auteur]
Groupe de Recherche sur les formes Injectables et les Technologies Associées (GRITA) - ULR 7365
Danel, Cecile [Auteur]
Groupe de Recherche sur les formes Injectables et les Technologies Associées (GRITA) - ULR 7365
Regnault, Romain [Auteur]
Groupe de Recherche sur les formes Injectables et les Technologies Associées - ULR 7365 [GRITA]
Vérité, Philippe [Auteur]
Université de Rouen Normandie [UNIROUEN]
Monteil, Christelle [Auteur]
Université de Rouen Normandie [UNIROUEN]
Foulon, Catherine [Auteur]
Groupe de Recherche sur les formes Injectables et les Technologies Associées (GRITA) - ULR 7365
Université de Rouen Normandie [UNIROUEN]
Rogez-Florent, Tiphaine [Auteur]
Université de Rouen Normandie [UNIROUEN]
Lecoeur, Marie [Auteur]

Groupe de Recherche sur les formes Injectables et les Technologies Associées (GRITA) - ULR 7365
Danel, Cecile [Auteur]

Groupe de Recherche sur les formes Injectables et les Technologies Associées (GRITA) - ULR 7365
Regnault, Romain [Auteur]
Groupe de Recherche sur les formes Injectables et les Technologies Associées - ULR 7365 [GRITA]
Vérité, Philippe [Auteur]
Université de Rouen Normandie [UNIROUEN]
Monteil, Christelle [Auteur]
Université de Rouen Normandie [UNIROUEN]
Foulon, Catherine [Auteur]

Groupe de Recherche sur les formes Injectables et les Technologies Associées (GRITA) - ULR 7365
Journal title :
Toxics
Abbreviated title :
Toxics
Volume number :
9
Pages :
200
Publication date :
2021-09
ISSN :
2305-6304
English keyword(s) :
gloves
liquid chromatography-diode array detector (HPLC-DAD)
gas chromatography-mass spectrometry (GC-MS)
alternative plasticizers
phthalates
liquid chromatography-diode array detector (HPLC-DAD)
gas chromatography-mass spectrometry (GC-MS)
alternative plasticizers
phthalates
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Gloves represent an essential feature for hand protection because it is a requirement in the professional framework to comply with both hand hygiene standards and the principles of good laboratory practice. Despite their ...
Show more >Gloves represent an essential feature for hand protection because it is a requirement in the professional framework to comply with both hand hygiene standards and the principles of good laboratory practice. Despite their wide use, there is a knowledge gap regarding their composition, including phthalates. The purpose of the present study was to develop two orthogonal methods, GC–MS and HPLC–DAD, for the screening of plasticizers in gloves. Performances of these two methods were compared in terms of ease of use, number of analyzed plasticizers, and sample preparation. The two methods were validated and applied for the identification and quantification of plasticizers in ten gloves made with different materials (vinyl, nitrile, latex, and neoprene). Results revealed the presence of three main ones: DEHP, DEHT, and DINP. Additionally, the contents of plasticizers were extremely variable, depending on the glove material. As expected, the results point out a predominant use of plasticizers in vinyl gloves with an amount that should be of concern. While DEHP is classified as a toxic substance for reproduction 1B, it was, however, quantified in the ten different glove samples studied. This study provides new data regarding the plasticizers’ content in protective gloves, which could be useful for risk assessment.Show less >
Show more >Gloves represent an essential feature for hand protection because it is a requirement in the professional framework to comply with both hand hygiene standards and the principles of good laboratory practice. Despite their wide use, there is a knowledge gap regarding their composition, including phthalates. The purpose of the present study was to develop two orthogonal methods, GC–MS and HPLC–DAD, for the screening of plasticizers in gloves. Performances of these two methods were compared in terms of ease of use, number of analyzed plasticizers, and sample preparation. The two methods were validated and applied for the identification and quantification of plasticizers in ten gloves made with different materials (vinyl, nitrile, latex, and neoprene). Results revealed the presence of three main ones: DEHP, DEHT, and DINP. Additionally, the contents of plasticizers were extremely variable, depending on the glove material. As expected, the results point out a predominant use of plasticizers in vinyl gloves with an amount that should be of concern. While DEHP is classified as a toxic substance for reproduction 1B, it was, however, quantified in the ten different glove samples studied. This study provides new data regarding the plasticizers’ content in protective gloves, which could be useful for risk assessment.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
CHU Lille
CHU Lille
Collections :
Submission date :
2023-05-25T02:59:15Z
2024-06-12T14:18:02Z
2024-06-12T14:18:02Z
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