Titre :

Diffusion Controlled Drug Delivery Systems

Auteur(s) :

Siepmann, Juergen [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008
Siegel, Ronald A. [Auteur]

Siepmann, Florence [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008

Éditeur(s) ou directeur(s) scientifique(s) :

Siepmann, Juergen
Siegel, Ronald A.
Rathbone, Michael J.

Titre de l’ouvrage :

Fundamentals and Applications of Controlled Release Drug Delivery

Numéro :

-

Titre du fascicule / de la collection :

Advances in Delivery Science and Technology

Pagination :

127-152

Éditeur :

Springer Link

Lieu de publication :

New York
NY

Date de publication :

2019-04-06

ISBN :

978-1-4614-0881-9

ISSN :

2192-6204

Mot(s)-clé(s) en anglais :

Drug Release
Apparent Diffusion Coefficient
Graft Copolymer
Drug Solubility
Fluorescence Recovery After Photobleaching

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

This chapter presents an overview on the different types of drug delivery systems that are predominantly governed by diffusion. The systems are classified according to their physical structure (reservoir devices versus ...
Lire la suite >This chapter presents an overview on the different types of drug delivery systems that are predominantly governed by diffusion. The systems are classified according to their physical structure (reservoir devices versus monolithic systems), as well as according to the ratio of “initial drug loading and drug solubility.” For various cases, mathematical models are briefly presented considering different device geometries. These theories are mechanistically realistic and enable quantitative description of the resulting release kinetics. Effects of formulation parameters on drug release can also be predicted quantitatively. Practical examples are given to illustrate the applicability of the presented theories and the benefits of understanding how a diffusion-controlled drug delivery system works.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Advanced Drug Delivery Systems (ADDS) - U1008

Date de dépôt :

2023-05-30T09:53:36Z
2024-02-23T10:19:34Z