Title :

Complexation of Terpenes for the Production of New Antimicrobial and Antibiofilm Molecules and Their Encapsulation in Order to Improve Their Activities

Author(s) :

El Fannassi, Yousra [Auteur]
Unité Matériaux et Transformations - UMR 8207 [UMET]
Abdelmalek Essaadi University [Tétouan] = Université Abdelmalek Essaadi [Tétouan] [UAE]
Gharsallaoui, Adem [Auteur]
Laboratoire d'automatique, de génie des procédés et de génie pharmaceutique [LAGEPP]
Khelissa, Simon [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
El Amrani, Mohamed Amin [Auteur]
Abdelmalek Essaadi University [Tétouan] = Université Abdelmalek Essaadi [Tétouan] [UAE]
Suisse, Isabelle [Auteur]
Unité de Catalyse et Chimie du Solide (UCCS) - UMR 8181
Sauthier, Mathieu [Auteur]
Unité de Catalyse et Chimie du Solide (UCCS) - UMR 8181
Jama, charafeddine [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207
Boudra, Saïd [Auteur]
Abdelmalek Essaadi University [Tétouan] = Université Abdelmalek Essaadi [Tétouan] [UAE]
Chihib, Nour-Eddine [Auteur]
Unité Matériaux et Transformations (UMET) - UMR 8207

Journal title :

Applied Sciences

Volume number :

13

Pages :

9854

Publisher :

MDPI

Publication date :

2023-08-31

ISSN :

2076-3417

English keyword(s) :

terpenes
metallic ions
complexes
microencapsulation
biofilm

HAL domain(s) :

Physique [physics]/Matière Condensée [cond-mat]/Science des matériaux [cond-mat.mtrl-sci]
Physique [physics]/Matière Condensée [cond-mat]/Matière Molle [cond-mat.soft]
Sciences de l'ingénieur [physics]/Génie des procédés
Sciences du Vivant [q-bio]/Ingénierie des aliments
Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Biologie moléculaire
Chimie/Matériaux
Chimie/Catalyse

English abstract : [en]

Microbiological risk associated with abiotic surfaces is one of the most important issues worldwide. Surface contaminations by pathogenic bacterial biofilms or adherent cells affect a number of sectors, including medical ...
Show more >Microbiological risk associated with abiotic surfaces is one of the most important issues worldwide. Surface contaminations by pathogenic bacterial biofilms or adherent cells affect a number of sectors, including medical services, food industries, human services, and the environment. There is a need to synthesize or to set up novel biosource-based antimicrobials. Terpenes such as limonene carvacrol are usually found in essential oils and have potent antimicrobial activities. However, the direct use of these molecules is often inefficient due to their low water solubility, loss of volatile compounds, thermal degradation, oxidation, and toxicity. The organic synthesis of stable metal complexes based on terpene ligands seems to be a promising issue, since it can allow for and promote the use of terpenes and challenge the drawbacks of these molecules. Spray drying could be the most suitable method for encapsulating metal complexes based on terpene ligands to protect and enhance their activity against bacterial biofilms. The goal of this review is to discuss the microbiological risk associated with pathogenic bacterial biofilm and the organic synthesis of novel antimicrobial complexes based on terpene ligands. In addition, this review explores how to improve their bioactivities and characteristics using a formulation based on encapsulation.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
CNRS
INRAE
ENSCL

Collections :

• Unité de Catalyse et Chimie du Solide (UCCS) - UMR 8181
• Unité Matériaux et Transformations (UMET) - UMR 8207

Research team(s) :

Processus aux Interfaces et Hygiène des Matériaux (PIHM)
Procédés de Recyclage et de Fonctionnalisation (PReF)
Catalyse et synthèse éco-compatible (CASECO)

Submission date :

2023-09-01T11:25:12Z
2023-09-05T07:52:42Z