Title :

Temporal trends in results of endovascular treatment of anterior intracranial large cerebral vessel occlusion: A 7-year study.

Author(s) :

Bourcier, Romain [Auteur]
Centre Hospitalier Universitaire de Nantes = Nantes University Hospital [CHU Nantes]
Consoli, Arturo [Auteur]
UFR Sciences de la santé Simone Veil [UVSQ Santé]
Desilles, Jean-Philippe [Auteur]
CHU Rothschild [AP-HP]
Labreuche, Julien [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Kyheng, Maéva [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Desal, Hubert [Auteur]
Centre Hospitalier Universitaire de Nantes = Nantes University Hospital [CHU Nantes]
Alias, Quentin [Auteur]
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
Gory, Benjamin [Auteur]
Centre Hospitalier Régional Universitaire de Nancy [CHRU Nancy]
Université de Lorraine [UL]
Dargazanli, Cyril [Auteur]
Centre Hospitalier Régional Universitaire [Montpellier] [CHRU Montpellier]
Janot, Kévin [Auteur]
Centre Hospitalier Régional Universitaire de Tours [CHRU Tours]
Zhu, François [Auteur]
Centre Hospitalier Régional Universitaire de Nancy [CHRU Nancy]
Université de Lorraine [UL]
Lapergue, Bertrand [Auteur]
UFR Sciences de la santé Simone Veil [UVSQ Santé]
Marnat, Gaultier [Auteur]

Journal title :

European Stroke Journal

Abbreviated title :

Eur Stroke J

Pages :

23969873231180338

Publication date :

2023-06-08

ISSN :

2396-9881

English keyword(s) :

Stroke
thrombectomy
device

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Background: Technical improvements in devices, changes in angiographic grading scales and various confounding factors have made difficult the detection of the temporal evolution of angiographic and clinical results after ...
Show more >Background: Technical improvements in devices, changes in angiographic grading scales and various confounding factors have made difficult the detection of the temporal evolution of angiographic and clinical results after endovascular treatment (EVT) for acute ischemic Stroke (AIS). We analyzed this evolution in time using the Endovascular Treatment in Ischemic Stroke (ETIS) registry. Materials and Methods: We analyzed the efficacy outcomes of EVT performed from January 2015 to January 2022, and modelized the temporal trends using mixed logistic regression models, further adjusted for age, intravenous thrombolysis prior to EVT, general anesthesia, occlusion site, balloon catheter use and the type of first-line EVT strategy. We assessed heterogeneity in temporal trends according to occlusion site, balloon catheter use, cardio embolic etiology, age (<80 years vs ⩾80 years) and first-line EVT strategy. Results: Among 6104 patients treated from 2015 to 2021, the rates of successful reperfusion (71.1%–89.6%) and of complete first pass effect (FPE) (4.6%–28.9%) increase, whereas the rates of patients with >3 EVT device passes (43.1%–17.5%) and favorable outcome (35.8%–28.9%) decrease significantly over time. A significant heterogeneity in temporal trends in successful reperfusion according to the first-line EVT strategy was found (p-het = 0.018). The temporal trend of increasing successful reperfusion rate was only significant in patients treated with contact aspiration in first-line (adjusted overall effect p = 0.010). Conclusion: In this 7-year-old large registry of ischemic stroke cases treated with EVT, we observed a significant increase with time in the rate of recanalization whereas there was a tendency toward a decrease in the rate of favorable outcome over the same period.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
CHU Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Submission date :

2023-11-15T01:49:21Z
2024-04-11T08:37:36Z