Title :

Surgical Risk Factors for Delayed Oral Feeding Autonomy in Patients with Left-Sided Congenital Diaphragmatic Hernia.

Author(s) :

Bourezma, Mélina [Auteur]
Hôpital Jeanne de Flandre [Lille]
Mur, Sébastien [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Hôpital Jeanne de Flandre [Lille]
Storme, Laurent [Auteur]
Hôpital Jeanne de Flandre [Lille]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Cailliau, Emeline [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Vaast, Pascal [Auteur]
Hôpital Jeanne de Flandre [Lille]
Sfeir, Rony [Auteur]
Hôpital Jeanne de Flandre [Lille]
Lauriot Dit Prevost, Arthur [Auteur]
Hôpital Jeanne de Flandre [Lille]
Aubry, Estelle [Auteur]
Hôpital Jeanne de Flandre [Lille]
Le Duc, Kévin [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Hôpital Jeanne de Flandre [Lille]
Sharma, Dyuti [Auteur]
Hôpital Jeanne de Flandre [Lille]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Journal title :

Journal of Clinical Medicine

Abbreviated title :

J Clin Med

Volume number :

12

Publication date :

2023-03-29

ISSN :

2077-0383

English keyword(s) :

congenital diaphragmatic hernia
failure to thrive
oral feeding autonomy
gastrostomy
surgical reintervention

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Background: Congenital diaphragmatic hernia (CDH) is a rare disease associated with major nutritional and digestive morbidities. Oral feeding autonomy remains a major issue for the care and management of these patients. ...
Show more >Background: Congenital diaphragmatic hernia (CDH) is a rare disease associated with major nutritional and digestive morbidities. Oral feeding autonomy remains a major issue for the care and management of these patients. The aim of this study was to specify the perinatal risk factors of delayed oral feeding autonomy in patients treated for CDH. Methods: This monocentric cohort study included 138 patients with CDH. Eighty-four patients were analyzed after the exclusion of 54 patients (11 with delayed postnatal diagnosis, 5 with chromosomal anomaly, 9 with genetic syndrom, 13 with right-sided CDH, and 16 who died before discharge and before oral feeding autonomy was acquired). They were divided into two groups: oral feeding autonomy at initial hospital discharge (group 1, n = 51) and nutritional support at discharge (group 2, n = 33). Antenatal, postnatal, and perisurgical data were analyzed from birth until first hospital discharge. To remove biased or redundant factors related to CDH severity, statistical analysis was adjusted according to the need for a patch repair. Results: After analysis and adjustment, delayed oral feeding autonomy was not related to observed/expected lung-to-head ratio (LHR o/e), intrathoracic liver and/or stomach position, or operative duration. After adjustment, prophylactic gastrostomy (OR adjusted: 16.3, IC 95%: 3.6–74.4) and surgical reoperation (OR adjusted: 5.1, IC 95% 1.1–23.7) remained significantly associated with delayed oral feeding autonomy. Conclusions: Delayed oral feeding autonomy occurred in more than one third of patients with CDH. Both prophylactic gastrostomy and surgical reoperation represent significant risk factors. Bowel obstruction might also impact oral feeding autonomy. Prophylactic gastrostomy seems to be a false “good idea” to prevent failure to thrive. This procedure should be indicated case per case. Bowel obstruction and all surgical reoperations represent decisive events that could impact oral feeding autonomy. Keywords: congenital diaphragmatic hernia; failure to thrive; oral feeding autonomy; gastrostomy; surgical reinterventionShow less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
CHU Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Submission date :

2023-11-15T02:16:32Z
2024-03-29T14:09:08Z