Risk factors for admission to the pediatric ...
Type de document :
Article dans une revue scientifique: Article original
DOI :
PMID :
URL permanente :
Titre :
Risk factors for admission to the pediatric critical care unit among children hospitalized with COVID-19 in France
Auteur(s) :
Prevost, Blandine [Auteur]
Mucoviscidose: physiopathologie et phénogénomique [CRSA]
Retbi, Aurélia [Auteur]
Assistance publique - Hôpitaux de Paris (AP-HP) [AP-HP]
Binder-Foucard, Florence [Auteur]
Les Hôpitaux Universitaires de Strasbourg [HUS]
Borde, Aurélie [Auteur]
CHU Bordeaux
Bruandet, Amelie [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Corvol, Harriet [Auteur]
Centre de Recherche Saint-Antoine [CRSA]
Gilleron, Véronique [Auteur]
Team MORPH3EUS [INSERM U1219 - UB - ISPED]
Le Bourhis-Zaimi, Maggie [Auteur]
Hospices Civils de Lyon [HCL]
Lenne, Xavier [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Muller, Joris [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Ouattara, Eric [Auteur]
CHU Bordeaux
Seguret, Fabienne [Auteur]
Centre Hospitalier Régional Universitaire [Montpellier] [CHRU Montpellier]
Loc, Pierre Tran Ba [Auteur]
Les Hôpitaux Universitaires de Strasbourg [HUS]
Du Montcel, Sophie T. [Auteur]
Institut du Cerveau = Paris Brain Institute [ICM]
Mucoviscidose: physiopathologie et phénogénomique [CRSA]
Retbi, Aurélia [Auteur]
Assistance publique - Hôpitaux de Paris (AP-HP) [AP-HP]
Binder-Foucard, Florence [Auteur]
Les Hôpitaux Universitaires de Strasbourg [HUS]
Borde, Aurélie [Auteur]
CHU Bordeaux
Bruandet, Amelie [Auteur]
![refId](/themes/Mirage2//images/idref.png)
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Corvol, Harriet [Auteur]
Centre de Recherche Saint-Antoine [CRSA]
Gilleron, Véronique [Auteur]
Team MORPH3EUS [INSERM U1219 - UB - ISPED]
Le Bourhis-Zaimi, Maggie [Auteur]
Hospices Civils de Lyon [HCL]
Lenne, Xavier [Auteur]
![refId](/themes/Mirage2//images/idref.png)
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Muller, Joris [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Ouattara, Eric [Auteur]
CHU Bordeaux
Seguret, Fabienne [Auteur]
Centre Hospitalier Régional Universitaire [Montpellier] [CHRU Montpellier]
Loc, Pierre Tran Ba [Auteur]
Les Hôpitaux Universitaires de Strasbourg [HUS]
Du Montcel, Sophie T. [Auteur]
Institut du Cerveau = Paris Brain Institute [ICM]
Titre de la revue :
Frontiers in Pediatrics
Nom court de la revue :
Front. Pediatr.
Numéro :
10
Pagination :
-
Date de publication :
2022-10-01
ISSN :
2296-2360
Mot(s)-clé(s) en anglais :
COVID-19
SARS-CoV-2
children
critical care
hospitalization
SARS-CoV-2
children
critical care
hospitalization
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Background: COVID-19 infection is less severe among children than among adults; however, some patients require hospitalization and even critical care. Using data from the French national medico-administrative database, we ...
Lire la suite >Background: COVID-19 infection is less severe among children than among adults; however, some patients require hospitalization and even critical care. Using data from the French national medico-administrative database, we estimated the risk factors for critical care unit (CCU) admissions among pediatric COVID-19 hospitalizations, the number and characteristics of the cases during the successive waves from January 2020 to August 2021 and described death cases. Methods: We included all children (age < 18) hospitalized with COVID-19 between January 1st, 2020, and August 31st, 2021. Follow-up was until September 30th, 2021 (discharge or death). Contiguous hospital stays were gathered in “care sequences.” Four epidemic waves were considered (cut off dates: August 11th 2020, January 1st 2021, and July 4th 2021). We excluded asymptomatic COVID-19 cases, post-COVID-19 diseases, and 1-day-long sequences (except death cases). Risk factors for CCU admission were assessed with a univariable and a multivariable logistic regression model in the entire sample and stratified by age, whether younger than 2. Results: We included 7,485 patients, of whom 1988 (26.6%) were admitted to the CCU. Risk factors for admission to the CCU were being younger than 7 days [OR: 3.71 95% CI (2.56–5.39)], being between 2 and 9 years old [1.19 (1.00–1.41)], pediatric multisystem inflammatory syndrome (PIMS) [7.17 (5.97–8.6)] and respiratory forms [1.26 (1.12–1.41)], and having at least one underlying condition [2.66 (2.36–3.01)]. Among hospitalized children younger than 2 years old, prematurity was a risk factor for CCU admission [1.89 (1.47–2.43)]. The CCU admission rate gradually decreased over the waves (from 31.0 to 17.8%). There were 32 (0.4%) deaths, of which the median age was 6 years (IQR: 177 days–15.5 years). Conclusion: Some children need to be more particularly protected from a severe evolution: newborns younger than 7 days old, children aged from 2 to 13 years who are more at risk of PIMS forms and patients with at least one underlying medical condition.Lire moins >
Lire la suite >Background: COVID-19 infection is less severe among children than among adults; however, some patients require hospitalization and even critical care. Using data from the French national medico-administrative database, we estimated the risk factors for critical care unit (CCU) admissions among pediatric COVID-19 hospitalizations, the number and characteristics of the cases during the successive waves from January 2020 to August 2021 and described death cases. Methods: We included all children (age < 18) hospitalized with COVID-19 between January 1st, 2020, and August 31st, 2021. Follow-up was until September 30th, 2021 (discharge or death). Contiguous hospital stays were gathered in “care sequences.” Four epidemic waves were considered (cut off dates: August 11th 2020, January 1st 2021, and July 4th 2021). We excluded asymptomatic COVID-19 cases, post-COVID-19 diseases, and 1-day-long sequences (except death cases). Risk factors for CCU admission were assessed with a univariable and a multivariable logistic regression model in the entire sample and stratified by age, whether younger than 2. Results: We included 7,485 patients, of whom 1988 (26.6%) were admitted to the CCU. Risk factors for admission to the CCU were being younger than 7 days [OR: 3.71 95% CI (2.56–5.39)], being between 2 and 9 years old [1.19 (1.00–1.41)], pediatric multisystem inflammatory syndrome (PIMS) [7.17 (5.97–8.6)] and respiratory forms [1.26 (1.12–1.41)], and having at least one underlying condition [2.66 (2.36–3.01)]. Among hospitalized children younger than 2 years old, prematurity was a risk factor for CCU admission [1.89 (1.47–2.43)]. The CCU admission rate gradually decreased over the waves (from 31.0 to 17.8%). There were 32 (0.4%) deaths, of which the median age was 6 years (IQR: 177 days–15.5 years). Conclusion: Some children need to be more particularly protected from a severe evolution: newborns younger than 7 days old, children aged from 2 to 13 years who are more at risk of PIMS forms and patients with at least one underlying medical condition.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
CHU Lille
CHU Lille
Date de dépôt :
2023-11-15T03:19:01Z
2024-05-13T06:53:23Z
2024-05-13T06:53:23Z
Fichiers
- fped-10-975826.pdf
- Non spécifié
- Accès libre
- Accéder au document