Scoring Systems for Organ Dysfunction and ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Scoring Systems for Organ Dysfunction and Multiple Organ Dysfunction: The PODIUM Consensus Conference.
Auteur(s) :
Schlapbach, Luregn J. [Auteur]
The University of Queensland [UQ [All campuses : Brisbane, Dutton Park Gatton, Herston, St Lucia and other locations]]
University Children’s Hospital Zurich
Weiss, Scott L. [Auteur]
Children’s Hospital of Philadelphia [CHOP ]
Bembea, Melania M. [Auteur]
Johns Hopkins University School of Medicine [Baltimore]
Carcillo, Joseph A. [Auteur]
Children's Hospital of Pittsburgh of UPMC [Etats-Unis]
Leclerc, Francis [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Leteurtre, Stephane [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Tissieres, Pierre [Auteur]
Hôpital Bicêtre [AP-HP, Le Kremlin-Bicêtre]
Wynn, James L. [Auteur]
The University of Florida College of Medicine
Zimmerman, Jerry [Auteur]
Seattle Children’s Hospital
Lacroix, Jacques [Auteur]
CHU Sainte Justine [Montréal]
The University of Queensland [UQ [All campuses : Brisbane, Dutton Park Gatton, Herston, St Lucia and other locations]]
University Children’s Hospital Zurich
Weiss, Scott L. [Auteur]
Children’s Hospital of Philadelphia [CHOP ]
Bembea, Melania M. [Auteur]
Johns Hopkins University School of Medicine [Baltimore]
Carcillo, Joseph A. [Auteur]
Children's Hospital of Pittsburgh of UPMC [Etats-Unis]
Leclerc, Francis [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Leteurtre, Stephane [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Tissieres, Pierre [Auteur]
Hôpital Bicêtre [AP-HP, Le Kremlin-Bicêtre]
Wynn, James L. [Auteur]
The University of Florida College of Medicine
Zimmerman, Jerry [Auteur]
Seattle Children’s Hospital
Lacroix, Jacques [Auteur]
CHU Sainte Justine [Montréal]
Titre de la revue :
Pediatrics
Nom court de la revue :
Pediatrics
Numéro :
149
Pagination :
S23-S31
Date de publication :
2022-01-04
ISSN :
1098-4275
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
CONTEXT
Multiple scores exist to characterize organ dysfunction in children.
OBJECTIVE
To review the literature on multiple organ dysfunction (MOD) scoring systems to estimate severity of illness and to characterize ...
Lire la suite >CONTEXT Multiple scores exist to characterize organ dysfunction in children. OBJECTIVE To review the literature on multiple organ dysfunction (MOD) scoring systems to estimate severity of illness and to characterize the performance characteristics of currently used scoring tools and clinical assessments for organ dysfunction in critically ill children. DATA SOURCES Electronic searches of PubMed and Embase were conducted from January 1992 to January 2020. STUDY SELECTION Studies were included if they evaluated critically ill children with MOD, evaluated the performance characteristics of scoring tools for MOD, and assessed outcomes related to mortality, functional status, organ-specific outcomes, or other patient-centered outcomes. DATA EXTRACTION Data were abstracted into a standard data extraction form by a task force member. RESULTS Of 1152 unique abstracts screened, 156 full text studies were assessed including a total of 54 eligible studies. The most commonly reported scores were the Pediatric Logistic Organ Dysfunction Score (PELOD), pediatric Sequential Organ Failure Assessment score (pSOFA), Pediatric Index of Mortality (PIM), PRISM, and counts of organ dysfunction using the International Pediatric Sepsis Definition Consensus Conference. Cut-offs for specific organ dysfunction criteria, diagnostic elements included, and use of counts versus weighting varied substantially. LIMITATIONS While scores demonstrated an increase in mortality associated with the severity and number of organ dysfunctions, the performance ranged widely. CONCLUSIONS The multitude of scores on organ dysfunction to assess severity of illness indicates a need for unified and data-driven organ dysfunction criteria, derived and validated in large, heterogenous international databases of critically ill children.Lire moins >
Lire la suite >CONTEXT Multiple scores exist to characterize organ dysfunction in children. OBJECTIVE To review the literature on multiple organ dysfunction (MOD) scoring systems to estimate severity of illness and to characterize the performance characteristics of currently used scoring tools and clinical assessments for organ dysfunction in critically ill children. DATA SOURCES Electronic searches of PubMed and Embase were conducted from January 1992 to January 2020. STUDY SELECTION Studies were included if they evaluated critically ill children with MOD, evaluated the performance characteristics of scoring tools for MOD, and assessed outcomes related to mortality, functional status, organ-specific outcomes, or other patient-centered outcomes. DATA EXTRACTION Data were abstracted into a standard data extraction form by a task force member. RESULTS Of 1152 unique abstracts screened, 156 full text studies were assessed including a total of 54 eligible studies. The most commonly reported scores were the Pediatric Logistic Organ Dysfunction Score (PELOD), pediatric Sequential Organ Failure Assessment score (pSOFA), Pediatric Index of Mortality (PIM), PRISM, and counts of organ dysfunction using the International Pediatric Sepsis Definition Consensus Conference. Cut-offs for specific organ dysfunction criteria, diagnostic elements included, and use of counts versus weighting varied substantially. LIMITATIONS While scores demonstrated an increase in mortality associated with the severity and number of organ dysfunctions, the performance ranged widely. CONCLUSIONS The multitude of scores on organ dysfunction to assess severity of illness indicates a need for unified and data-driven organ dysfunction criteria, derived and validated in large, heterogenous international databases of critically ill children.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
CHU Lille
CHU Lille
Date de dépôt :
2023-11-15T05:13:17Z
2024-01-10T15:22:42Z
2024-01-10T15:22:42Z