Predictors of Favorable Outcome after ...
Type de document :
Article dans une revue scientifique: Article original
DOI :
PMID :
URL permanente :
Titre :
Predictors of Favorable Outcome after Endovascular Thrombectomy in MRI: Selected Patients with Acute Basilar Artery Occlusion.
Auteur(s) :
Mahmoudi, M. [Auteur]
Dargazanli, C. [Auteur]
Département de Neuroradiologie[Montpellier]
Cagnazzo, Federico [Auteur]
Département de Neuroradiologie[Montpellier]
Derraz, Imad [Auteur]
Département de Neuroradiologie[Montpellier]
Arquizan, Caroline [Auteur]
Département de Neuroradiologie[Montpellier]
Wacogne, Anne [Auteur]
Service de Neurologie [CHU Nimes] [Pôle NIRR]
Labreuche, Julien [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Bonafe, Alain [Auteur]
Institut des Neurosciences de Montpellier [INM]
Département de Neuroradiologie[Montpellier]
Sablot, Denis [Auteur]
Centre Hospitalier Saint Jean de Perpignan
Lefevre, Pierre-Henri [Auteur]
Département de Neuroradiologie[Montpellier]
Gascou, Gregory [Auteur]
Département de Neuroradiologie[Montpellier]
Gaillard, Nicolas [Auteur]
Département de neurologie [Montpellier]
Scott, C. [Auteur]
Département d'anesthésie-réanimation[Montpellier]
Costalat, Vincent [Auteur]
Département de Neuroradiologie[Montpellier]
Mourand, Isabelle [Auteur]
Département de neurologie [Montpellier]
Dargazanli, C. [Auteur]
Département de Neuroradiologie[Montpellier]
Cagnazzo, Federico [Auteur]
Département de Neuroradiologie[Montpellier]
Derraz, Imad [Auteur]
Département de Neuroradiologie[Montpellier]
Arquizan, Caroline [Auteur]
Département de Neuroradiologie[Montpellier]
Wacogne, Anne [Auteur]
Service de Neurologie [CHU Nimes] [Pôle NIRR]
Labreuche, Julien [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Bonafe, Alain [Auteur]
Institut des Neurosciences de Montpellier [INM]
Département de Neuroradiologie[Montpellier]
Sablot, Denis [Auteur]
Centre Hospitalier Saint Jean de Perpignan
Lefevre, Pierre-Henri [Auteur]
Département de Neuroradiologie[Montpellier]
Gascou, Gregory [Auteur]
Département de Neuroradiologie[Montpellier]
Gaillard, Nicolas [Auteur]
Département de neurologie [Montpellier]
Scott, C. [Auteur]
Département d'anesthésie-réanimation[Montpellier]
Costalat, Vincent [Auteur]
Département de Neuroradiologie[Montpellier]
Mourand, Isabelle [Auteur]
Département de neurologie [Montpellier]
Titre de la revue :
American Journal of Neuroradiology
Nom court de la revue :
AJNR Am J Neuroradiol
Date de publication :
2020-08-22
ISSN :
1936-959X
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
BACKGROUND AND PURPOSE: Clinical outcomes after endovascular treatment for acute basilar artery occlusions need further investigation. Our aim was to analyze predictors of a 90-day good functional outcome defined as mRS ...
Lire la suite >BACKGROUND AND PURPOSE: Clinical outcomes after endovascular treatment for acute basilar artery occlusions need further investigation. Our aim was to analyze predictors of a 90-day good functional outcome defined as mRS 0–2 after endovascular treatment in MR imaging–selected patients with acute basilar artery occlusions. MATERIALS AND METHODS: We analyzed consecutive MR imaging–selected patients with acute basilar artery occlusions endovascularly treated within the first 24 hours after symptom onset. Successful and complete reperfusion was defined as modified TICI scores 2b–3 and 3, respectively. Outcome at 90 days was analyzed in univariate and multivariate analysis regarding baseline patient treatment characteristics and periprocedural outcomes. RESULTS: One hundred ten patients were included. In 10 patients, endovascular treatment was aborted for failed proximal/distal access. Overall, successful reperfusion was achieved in 81.8% of cases (n = 90; 95% CI, 73.3%–88.6%). At 90 days, favorable outcome was 31.8%, with a mortality rate of 40.9%; the prevalence of symptomatic intracranial hemorrhage within 24 hours was 2.7%. The median time from symptom onset to groin puncture was 410 minutes (interquartile range, 280–540 minutes). In multivariable analysis, complete reperfusion (OR = 6.59; 95% CI, 2.17–20.03), lower pretreatment NIHSS (OR = 0.77; 95% CI, 0.64–0.94), the presence of posterior communicating artery collateral flow (OR = 2.87; 95% CI, 1.05–7.84), the absence of atrial fibrillation (OR = 0.18; 95% CI, 0.03–0.99), and intravenous thrombolysis administration (OR = 2.75; 95% CI, 1.04–7.04) were associated with 90-day favorable outcome. CONCLUSIONS: In our series of MR imaging–selected patients with acute basilar artery occlusions, complete reperfusion was the strongest predictor of a good outcome. Lower pretreatment NIHSS, the presence of posterior communicating artery collateral flow, the absence of atrial fibrillation, and intravenous thrombolysis administration were associated with favorable outcome.Lire moins >
Lire la suite >BACKGROUND AND PURPOSE: Clinical outcomes after endovascular treatment for acute basilar artery occlusions need further investigation. Our aim was to analyze predictors of a 90-day good functional outcome defined as mRS 0–2 after endovascular treatment in MR imaging–selected patients with acute basilar artery occlusions. MATERIALS AND METHODS: We analyzed consecutive MR imaging–selected patients with acute basilar artery occlusions endovascularly treated within the first 24 hours after symptom onset. Successful and complete reperfusion was defined as modified TICI scores 2b–3 and 3, respectively. Outcome at 90 days was analyzed in univariate and multivariate analysis regarding baseline patient treatment characteristics and periprocedural outcomes. RESULTS: One hundred ten patients were included. In 10 patients, endovascular treatment was aborted for failed proximal/distal access. Overall, successful reperfusion was achieved in 81.8% of cases (n = 90; 95% CI, 73.3%–88.6%). At 90 days, favorable outcome was 31.8%, with a mortality rate of 40.9%; the prevalence of symptomatic intracranial hemorrhage within 24 hours was 2.7%. The median time from symptom onset to groin puncture was 410 minutes (interquartile range, 280–540 minutes). In multivariable analysis, complete reperfusion (OR = 6.59; 95% CI, 2.17–20.03), lower pretreatment NIHSS (OR = 0.77; 95% CI, 0.64–0.94), the presence of posterior communicating artery collateral flow (OR = 2.87; 95% CI, 1.05–7.84), the absence of atrial fibrillation (OR = 0.18; 95% CI, 0.03–0.99), and intravenous thrombolysis administration (OR = 2.75; 95% CI, 1.04–7.04) were associated with 90-day favorable outcome. CONCLUSIONS: In our series of MR imaging–selected patients with acute basilar artery occlusions, complete reperfusion was the strongest predictor of a good outcome. Lower pretreatment NIHSS, the presence of posterior communicating artery collateral flow, the absence of atrial fibrillation, and intravenous thrombolysis administration were associated with favorable outcome.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
CHU Lille
CHU Lille
Date de dépôt :
2023-11-15T08:17:41Z
2023-12-05T12:26:07Z
2023-12-05T12:26:07Z
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