Is the Severity of the Clinical Expression ...
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Article dans une revue scientifique: Article original
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Title :
Is the Severity of the Clinical Expression of Anorexia Nervosa Influenced by an Anxiety, Depressive, or Obsessive-Compulsive Comorbidity Over a Lifetime?
Author(s) :
Riquin, Elise [Auteur]
Centre Hospitalier Universitaire d'Angers [CHU Angers]
Laboratoire de Psychologie des Pays de la Loire [LPPL]
Raynal, Agathe [Auteur]
CHU Rouen
Mattar, Lama [Auteur]
Department of Natural Sciences [Lebanese American University] [NS/SAS/LAU]
Lalanne, Christophe [Auteur]
Université Paris Diderot, Sorbonne Paris Cité, Paris, France
Hirot, France [Auteur]
Institut Mutualiste de Montsouris [IMM]
Centre de recherche en épidémiologie et santé des populations [CESP]
Huas, Caroline [Auteur]
Centre de recherche en épidémiologie et santé des populations [CESP]
Duclos - Lavagne D'ortigue, Jeanne [Auteur]
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Berthoz, Sylvie [Auteur]
Institut mutualiste Monsouris [IMM]
Université de Versailles Saint-Quentin-en-Yvelines [UVSQ]
Godart, Nathalie [Auteur]
Centre de recherche en épidémiologie et santé des populations [CESP]
Institut Mutualiste de Montsouris [IMM]
Centre Hospitalier Universitaire d'Angers [CHU Angers]
Laboratoire de Psychologie des Pays de la Loire [LPPL]
Raynal, Agathe [Auteur]
CHU Rouen
Mattar, Lama [Auteur]
Department of Natural Sciences [Lebanese American University] [NS/SAS/LAU]
Lalanne, Christophe [Auteur]
Université Paris Diderot, Sorbonne Paris Cité, Paris, France
Hirot, France [Auteur]
Institut Mutualiste de Montsouris [IMM]
Centre de recherche en épidémiologie et santé des populations [CESP]
Huas, Caroline [Auteur]
Centre de recherche en épidémiologie et santé des populations [CESP]
Duclos - Lavagne D'ortigue, Jeanne [Auteur]
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Berthoz, Sylvie [Auteur]
Institut mutualiste Monsouris [IMM]
Université de Versailles Saint-Quentin-en-Yvelines [UVSQ]
Godart, Nathalie [Auteur]
Centre de recherche en épidémiologie et santé des populations [CESP]
Institut Mutualiste de Montsouris [IMM]
Journal title :
Frontiers in Psychiatry
Abbreviated title :
Front. Psychiatry
Volume number :
12
Publisher :
Frontiers Media SA
Publication date :
2021-07-01
ISSN :
1664-0640
English keyword(s) :
anorexia nervosa
anxiety
body mass index
depression
nutritional status
anxiety
body mass index
depression
nutritional status
HAL domain(s) :
Sciences cognitives
English abstract : [en]
Purpose: The relationship between anxiety or depressive comorbidities, their chronology of onset, and the severity of anorexia nervosa (AN) is not well-studied. We hypothesize that the existence of a comorbidity, particularly ...
Show more >Purpose: The relationship between anxiety or depressive comorbidities, their chronology of onset, and the severity of anorexia nervosa (AN) is not well-studied. We hypothesize that the existence of a comorbidity, particularly before the onset of AN, is associated with greater severity of AN.Methods: One hundred seventy-seven subjects were assessed. The prevalence of major depressive disorder (MDD), obsessive-compulsive disorder (OCD), generalized anxiety disorder (GAD), and social phobia (SP) as well as their chronology of onset were studied. The assessment criteria of AN severity were the overall clinical condition, body mass index (BMI) on admission, lowest BMI, intensity of the eating symptoms, age at the onset of AN, illness duration, number of hospitalizations, and quality of life.Results: Patients with AN had the greatest clinical severity when they had a comorbid disorder over their lifetime, such as MDD, GAD, or SP. These comorbidities along with OCD were associated with a higher level of eating symptoms and a more altered quality of life. A profile of maximum severity was associated with a higher prevalence of MDD and GAD. Concerning the chronology of onset, the age at the start of AN was later in cases of MDD or GAD prior to AN.Conclusion: There seems to be an association between severity of AN and both MDD and GAD. The chronology of onset of the comorbidity did not seem to be associated with the severity.Show less >
Show more >Purpose: The relationship between anxiety or depressive comorbidities, their chronology of onset, and the severity of anorexia nervosa (AN) is not well-studied. We hypothesize that the existence of a comorbidity, particularly before the onset of AN, is associated with greater severity of AN.Methods: One hundred seventy-seven subjects were assessed. The prevalence of major depressive disorder (MDD), obsessive-compulsive disorder (OCD), generalized anxiety disorder (GAD), and social phobia (SP) as well as their chronology of onset were studied. The assessment criteria of AN severity were the overall clinical condition, body mass index (BMI) on admission, lowest BMI, intensity of the eating symptoms, age at the onset of AN, illness duration, number of hospitalizations, and quality of life.Results: Patients with AN had the greatest clinical severity when they had a comorbid disorder over their lifetime, such as MDD, GAD, or SP. These comorbidities along with OCD were associated with a higher level of eating symptoms and a more altered quality of life. A profile of maximum severity was associated with a higher prevalence of MDD and GAD. Concerning the chronology of onset, the age at the start of AN was later in cases of MDD or GAD prior to AN.Conclusion: There seems to be an association between severity of AN and both MDD and GAD. The chronology of onset of the comorbidity did not seem to be associated with the severity.Show less >
Language :
Anglais
Peer reviewed article :
Oui
Audience :
Internationale
Other project(s) or funding source(s) :
Agence Nationale de la Recherche, ANR Institut National de la Santé et de la Recherche Médicale, Inserm Fondation de France Ministère des Affaires Sociales et de la Santé
EVHAN study was supported by grants from the French Ministry of Health (PHRCN 2007, 2011 AOM11197; ANR Jeune chercheur, Bourse de thèse Eiffel) and from CNAM-TS, Fondation de France, Fondation MGEN, EHESP, AP-HP, CIFRE, and Contrats d’interface INSERM.
EVHAN study was supported by grants from the French Ministry of Health (PHRCN 2007, 2011 AOM11197; ANR Jeune chercheur, Bourse de thèse Eiffel) and from CNAM-TS, Fondation de France, Fondation MGEN, EHESP, AP-HP, CIFRE, and Contrats d’interface INSERM.
Administrative institution(s) :
Université de Lille
CNRS
CHU Lille
CNRS
CHU Lille
Research team(s) :
Équipe Dynamique Émotionnelle et Pathologies (DEEP)
Submission date :
2023-11-17T15:24:11Z
2023-11-22T16:53:25Z
2023-11-22T16:53:25Z
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