Fundamental and Advanced Therapies, Vaccine Development against SARS-CoV-2.

Hudakova, N.; Hricikova, S.; Kulkarni, A.; Bhide, M.; Kontsekova, E.; Cizkova, Dasa

Document type :

Article dans une revue scientifique: Article de synthèse/Review paper

DOI :

10.3390/pathogens10060636

PMID :

34064300

Permalink :

http://hdl.handle.net/20.500.12210/92646

Title :

Fundamental and Advanced Therapies, Vaccine Development against SARS-CoV-2.

Author(s) :

Hudakova, N. [Auteur]
Hricikova, S. [Auteur]
Kulkarni, A. [Auteur]
Bhide, M. [Auteur]
Kontsekova, E. [Auteur]
Cizkova, Dasa [Auteur]

Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192

Journal title :

Pathogens

Abbreviated title :

Pathogens

Volume number :

Publication date :

2021-06-11

ISSN :

2076-0817

English keyword(s) :

SARS-CoV-2
COVID-19
cytokine storm
therapy
antibodies
vaccines

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Coronavirus disease (COVID-19) caused by the SARS-CoV-2 virus has been affecting the world since the end of 2019. The severity of the disease can range from an asymptomatic or mild course to acute respiratory distress ...
Show more >Coronavirus disease (COVID-19) caused by the SARS-CoV-2 virus has been affecting the world since the end of 2019. The severity of the disease can range from an asymptomatic or mild course to acute respiratory distress syndrome (ARDS) with respiratory failure, which may lead to death. Since the outbreak of the pandemic, scientists around the world have been studying the genome and molecular mechanisms of SARS-CoV-2 infection to develop effective therapies and prevention. In this review, we summarize the progressive development of various treatments and vaccines as they have emerged, a year after the outbreak of the pandemic. Initially for COVID-19, patients were recommended drugs with presumed antiviral, anti-inflammatory, and antimicrobial effects that were previously used to treat other diseases. Thereafter, therapeutic interventions were supplemented with promising approaches based on antibodies, peptides, and stem cells. However, licensed COVID-19 vaccines remain the most effective weapon in combating the pandemic. While there is an enormous effort to enhance the vaccination rate to increase the entire population immunity, the production and delivery of vaccines is becoming limited in several countries. In this regard, there are new challenges needing to be addressed by combining non-pharmacological intervention with effective therapies until vaccination is accessible to all.Show less >

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192

Submission date :

2023-12-13T04:55:48Z
2024-01-31T10:45:37Z

Files

pathogens-10-00636-v3.pdf
Version éditeur
Open access
Access the document

Except where otherwise noted, this item's license is described as Attribution 3.0 United States

Version	Link	Modification date
2	20.500.12210/92646*	2024-01-31T10:43:47Z
1	20.500.12210/92646.1	2023-12-13T04:55:48Z

Fundamental and Advanced Therapies, Vaccine ...

BibTeX

CSV

Excel

RIS

Files

Version history

Fundamental and Advanced Therapies, Vaccine ... BibTeX CSV Excel RIS

Files

Version history

Fundamental and Advanced Therapies, Vaccine ...

BibTeX

CSV

Excel

RIS