Title :

Aortic dissection: results of the invasive treatment in France between 2012 and 2018 according to the French national database

Author(s) :

Lejot, Anais [Auteur]
Université de Lille
Ledieu, Guillaume [Auteur]
Institut Coeur Poumon [CHU Lille]
Lenne, Xavier [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Bruandet, Amelie [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Delsart, Pascal [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Girard, Audrey [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Patterson, Benjamin [Auteur]
University Hospital Southampton NHS Foundation Trust
Sobocinski, Jonathan [Auteur]
Advanced Drug Delivery Systems (ADDS) - U1008

Journal title :

Journal of Cardiovascular Surgery

Abbreviated title :

J. Cardiovasc. Surg.

Volume number :

64

Pages :

-

Publication date :

2023-11-29

ISSN :

0021-9509

English keyword(s) :

Aortic dissection
Aortic diseases
Data collection

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

BACKGROUND: To evaluate results of the invasive repair in the management of acute aortic dissection (AoD) in France. METHODS: Patients admitted to hospital with acute AoD from 2012 to 2018 were identified. Patient ...
Show more >BACKGROUND: To evaluate results of the invasive repair in the management of acute aortic dissection (AoD) in France. METHODS: Patients admitted to hospital with acute AoD from 2012 to 2018 were identified. Patient demographics, severity score at admission, treatment strategy and in-hospital mortality were described. For patients undergoing intervention, perioperative complications rate was reported. A secondary analysis evaluating patients’ outcome as regards of the annual caseload per center was conducted. RESULTS: Overall, 14,706 patients with acute AoD were identified (male 64%, mean age 67, median modified Elixhauser score 5). The overall incidence increased during the study period (from 3.8 in 2012 to 4.4/100,000 in 2018) associated with a North-South gradient (respectively 3.6 vs. 4.7/100,000) and a winter peak; 45.5% (N.=6697) of patients received medical treatment alone. Among those with invasive repair, 6276 (78.3%) were defined as type A AoD (TAAD), whereas type B AoD (TBAD) accounted for 1733 patients (21.7%), of whom 1632 (94%) had TEVAR and 101 (6%) had other arterial procedures; 30-day mortality was respectively 18.9% in TAAD and 9.5% for TBAD. In high-volume centers (i.e. >20 AoD/year), a lower 3-month mortality of 22.3% was noted compared to 31.4% in the low-volume centres (P<0.001); 47% of patients reported ≥1 early major complication. TEVAR exhibited less complication (P<0.001) compared to other arterial reconstructions in TBAD. CONCLUSIONS: The incidence of acute AoD increased in France over the period of the study and was associated with stable postoperative early mortality. Early postoperative mortality is significantly reduced in high-volume centers.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Advanced Drug Delivery Systems (ADDS) - U1008
• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Submission date :

2023-12-15T05:19:04Z
2024-02-26T09:38:49Z