Extensive Necrotic Purpura in Levamisole ...
Document type :
Article dans une revue scientifique: Article original
DOI :
PMID :
Title :
Extensive Necrotic Purpura in Levamisole-Adulterated Cocaine Abuse - A Case Report
Author(s) :
Le Garff, Erwan [Auteur]
Unité de Taphonomie médico-légale et Anatomie - ULR 7367 [UTML&A]
Tournel, Gilles [Auteur]
Aliments Bioprocédés Toxicologie Environnements [ABTE]
Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
Becquart, Coralie [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Cottencin, Olivier [Auteur]
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Dupin, Nicolas [Auteur]
Parallel Cooperative Multi-criteria Optimization [DOLPHIN]
Delaporte, Emmanuel [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Hédouin, Valéry [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]

Unité de Taphonomie médico-légale et Anatomie - ULR 7367 [UTML&A]
Tournel, Gilles [Auteur]
Aliments Bioprocédés Toxicologie Environnements [ABTE]
Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
Becquart, Coralie [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Cottencin, Olivier [Auteur]

Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Dupin, Nicolas [Auteur]
Parallel Cooperative Multi-criteria Optimization [DOLPHIN]
Delaporte, Emmanuel [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Hédouin, Valéry [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Journal title :
Journal of Forensic Sciences
Pages :
1681-1685
Publisher :
Wiley
Publication date :
2016-11
English keyword(s) :
Legal medicine
Cocaine
Forensic science
Toxicology
Necrotic purpura
Levamisole
Cocaine
Forensic science
Toxicology
Necrotic purpura
Levamisole
HAL domain(s) :
Sciences du Vivant [q-bio]/Médecine humaine et pathologie
English abstract : [en]
Levamisole, which is used as an adulterated compound of cocaine, is currently being seen year after year in cocaine intoxication. For a few cases in the last decade, necrotic purpura and neutropenia after levamisole/cocaine ...
Show more >Levamisole, which is used as an adulterated compound of cocaine, is currently being seen year after year in cocaine intoxication. For a few cases in the last decade, necrotic purpura and neutropenia after levamisole/cocaine intoxication have been described in the medical community. Herein, we present an original case of levamisole intoxication of a 40-year-old woman who smoked heroin and cocaine few during a month. She rapidly presented an extensive necrotic purpura of the nose, cheeks and extremities (lower and upper), and immunologic reactions (positive anti-MPO and anti-HNE). Levamisole was detected on hairs with ultra-high performance liquid chromatography and tandem mass spectrometry. The case reports also a probable cocaine supplier deceit, which bring pure drug for hospital investigation after the intoxication of his client. The intoxicated woman had survived with several skin and chronic pain complications. That case recalls the knowledge about levamisole with a short review of the forensic literature.Show less >
Show more >Levamisole, which is used as an adulterated compound of cocaine, is currently being seen year after year in cocaine intoxication. For a few cases in the last decade, necrotic purpura and neutropenia after levamisole/cocaine intoxication have been described in the medical community. Herein, we present an original case of levamisole intoxication of a 40-year-old woman who smoked heroin and cocaine few during a month. She rapidly presented an extensive necrotic purpura of the nose, cheeks and extremities (lower and upper), and immunologic reactions (positive anti-MPO and anti-HNE). Levamisole was detected on hairs with ultra-high performance liquid chromatography and tandem mass spectrometry. The case reports also a probable cocaine supplier deceit, which bring pure drug for hospital investigation after the intoxication of his client. The intoxicated woman had survived with several skin and chronic pain complications. That case recalls the knowledge about levamisole with a short review of the forensic literature.Show less >
Language :
Anglais
Peer reviewed article :
Oui
Audience :
Internationale
Popular science :
Non
Source :
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