Title :

Comparison of clinical profiles and care for patients with incident versus recurrent acute coronary syndromes in France: data from the MONICA registries

Author(s) :

Machta, Suzanne [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Gauthier, Victoria [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Ferrières, Jean [Auteur]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Equipe Vieillissement (CERPOP)
Montaye, Michèle [Auteur]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Huo Yung Kai, Samantha [Auteur]
Equipe Vieillissement (CERPOP)
Gbokou, Stefy [Auteur]
Université de Strasbourg [UNISTRA]
Biasch, Katia [Auteur]
Université de Strasbourg [UNISTRA]
Moitry, Marie [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Université de Strasbourg [UNISTRA]
Amouyel, Philippe [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Dallongeville, Jean [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Meirhaeghe, Aline [Auteur correspondant]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]

Journal title :

PLOS ONE

Pages :

e0263589

Publisher :

Public Library of Science

Publication date :

2022-02-14

ISSN :

1932-6203

English keyword(s) :

acute coronary syndrome
mortality
morbidity
registry
STEMI
NSTEMI
incident event
recurrent event

HAL domain(s) :

Sciences du Vivant [q-bio]/Santé publique et épidémiologie
Statistiques [stat]
Sciences du Vivant [q-bio]

English abstract : [en]

Background: Recurrence is common after an acute coronary syndrome (ACS). In order to better assess the prognosis for patients with ACS, we compared clinical profiles, treatments, and case fatality rates for incident vs. ...
Show more >Background: Recurrence is common after an acute coronary syndrome (ACS). In order to better assess the prognosis for patients with ACS, we compared clinical profiles, treatments, and case fatality rates for incident vs. recurrent ACS.Methods: We enrolled 1,459 men and women (age: 35-74) living in three geographical areas covered by French MONICA registries and who had been admitted to hospital for an ACS in 2015/2016. We recorded and compared the clinical characteristics and medical care for patients with an incident vs. a recurrent ACS.Results: Overall, 431 (30%) had a recurrent ACS. Relative to patients with an incident ACS, patients with recurrence were older (p<0.0001), had a greater frequency of NSTEMI or UA (p<0.0001), were less likely to show typical symptoms (p = 0.045), were more likely to have an altered LVEF (p<0.0001) and co-morbidities. Angioplasty was less frequently performed among patients with recurrent than incident NSTEMI (p<0.05). There were no intergroup differences in the prescription of the recommended secondary prevention measures upon hospital discharge, except for functional rehabilitation more frequently prescribed among incident patients (p<0.0001). Although the crude 1-year mortality rate was higher for recurrent cases (14%) than for incident cases (8%) (p<0.05), this difference was no longer significant after adjustment for age, sex, region, diagnosis category and LVEF.Conclusion: Compared with incident patients, recurrent cases were more likely to have co-morbidities and to have suboptimal treatments prior to hospital stay, reinforcing the need for secondary prevention.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Collections :

• Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement (RID-AGE) - U1167

Source :

Harvested from HAL