Title :

Dual infections by influenza A/H3N2 and B viruses and by influenza A/H3N2 and A/H1N1 viruses during winter 2007, Corsica Island, France.

Author(s) :

Falchi, A. [Auteur]
Laboratoire « Sciences pour l’Environnement » (UMR CNRS 6134 SPE) [SPE]
Arena, C. [Auteur]
Andreoletti, L. [Auteur]
Service maladies infectueuses
Jacques, Julien [Auteur]
Laboratoire Paul Painlevé - UMR 8524 [LPP]
Leveque, N. [Auteur]
Virologie et pathogenèse virale [VPV]
Blanchon, T. [Auteur]
Lina, B. [Auteur]
Virologie et pathogenèse virale [VPV]
Turbelin, C. [Auteur]
Dorléans, Y. [Auteur]
Flahault, A. [Auteur]
CHU Tenon [AP-HP]
Amoros, J. P. [Auteur]
Spadoni, G. [Auteur]
Agostini, F. [Auteur]
Varesi, L. [Auteur]
Laboratoire « Sciences pour l’Environnement » (UMR CNRS 6134 SPE) [SPE]

Journal title :

Journal of Clinical Virology

Pages :

148-51

Publisher :

Elsevier

Publication date :

2008-02

ISSN :

1386-6532

HAL domain(s) :

Sciences du Vivant [q-bio]/Génétique/Génétique des populations [q-bio.PE]

English abstract : [en]

BACKGROUND: The investigation of dual influenza infection human cases is of major interest specifically for the control of new emerging influenza strains. OBJECTIVES: Using RT-PCR assays, we retrospectively assessed the ...
Show more >BACKGROUND: The investigation of dual influenza infection human cases is of major interest specifically for the control of new emerging influenza strains. OBJECTIVES: Using RT-PCR assays, we retrospectively assessed the prevalence of dual influenza virus infections that occurred in patients during the 2006-2007 winter season in Corsica Island (France). STUDY DESIGN: One hundred and thirty-four nasal swabbing samples taken from patients suffering from influenza-like illness between February and March 2007 were analysed using a rapid influenza antigen detection test, cell culture and RT-PCR assays. RESULTS AND CONCLUSION: Influenza viruses were detected in 93 (69.4%) of 134 patients with influenza-like illness using the combination of classical and molecular assays. Dual respiratory infections by influenza viruses were detected in 3 (3.2%) of the 93 influenza positive patients, including two cases of infection by influenza A/H3N2 and B viruses and one case of dual infection by influenza A/H3N2 and A/H1N1 viruses. In the present report, human co-infection cases by two influenza viruses appeared as a rare event in symptomatic patients. However, the virological and epidemiological mechanisms that determine the occurrence of dual influenza infections remain to be fully investigated in further prospective multicentric studies.Show less >

Language :

Anglais

Popular science :

Non

Collections :

• Laboratoire Paul Painlevé - UMR 8524

Source :

Harvested from HAL