Title :

French guidelines for the etiological workup of eosinophilia and the management of hypereosinophilic syndromes.

Author(s) :

Groh, Matthieu [Auteur]
Hôpital Foch [Suresnes]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Hôpital Ambroise Paré [AP-HP]
Institute for Translational Research in Inflammation - U 1286 [INFINITE]
Rohmer, Julien [Auteur]
Hôpital Foch [Suresnes]
Hôpital Ambroise Paré [AP-HP]
CIC - CHU Bichat
Etienne, Nicolas [Auteur]
Hôpital Necker - Enfants Malades [AP-HP]
Hôpital Ambroise Paré [AP-HP]
Abou Chahla, Wadih [Auteur]
Hôpital Foch [Suresnes]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Hôpital Ambroise Paré [AP-HP]
Baudet, Antoine [Auteur]
Hôpital Foch [Suresnes]
Centre Hospitalier Annecy-Genevois [Saint-Julien-en-Genevois]
Hôpital Ambroise Paré [AP-HP]
Chan Hew Wai, Aurélie [Auteur]
Hôpital Foch [Suresnes]
Hôpital Ambroise Paré [AP-HP]
Chenivesse, Cecile [Auteur]
Hôpital Foch [Suresnes]
Hôpital Ambroise Paré [AP-HP]
Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 9017
Clisson Rusek, Irena [Auteur]
Hôpital Ambroise Paré [AP-HP]
Cottin, Vincent [Auteur]
Hospices Civils de Lyon [HCL]
Hôpital Ambroise Paré [AP-HP]
Decamp, Matthieu [Auteur]
Hôpital Ambroise Paré [AP-HP]
CHU Caen
De Groote, Pascal [Auteur]
Hôpital Foch [Suresnes]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Hôpital Ambroise Paré [AP-HP]
Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement (RID-AGE) - U1167
Delahousse, Fanny [Auteur]
Hôpital Ambroise Paré [AP-HP]
Duployez, Nicolas [Auteur]
Cancer Heterogeneity, Plasticity and Resistance to Therapies (CANTHER) - UMR 9020 - UMR 1277
Hôpital Foch [Suresnes]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Hôpital Ambroise Paré [AP-HP]
Faguer, Stanislas [Auteur]
Université Toulouse III - Paul Sabatier [UT3]
Hôpital Ambroise Paré [AP-HP]
Gottrand, fréderic [Auteur]
Hôpital Foch [Suresnes]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Hôpital Ambroise Paré [AP-HP]
Institute for Translational Research in Inflammation - U 1286 [INFINITE]
Huang, Florent [Auteur]
Hôpital Foch [Suresnes]
Hôpital Ambroise Paré [AP-HP]
Leblanc, Thierry [Auteur]
Hôpital Ambroise Paré [AP-HP]
Hôpital Robert Debré
Magnan, Antoine [Auteur]
Hôpital Foch [Suresnes]
Hôpital Ambroise Paré [AP-HP]
Martin, Thierry [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Hôpital Foch [Suresnes]
Hôpital Ambroise Paré [AP-HP]
Mortuaire, Geoffrey [Auteur]
Hôpital Foch [Suresnes]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Hôpital Ambroise Paré [AP-HP]
Institute for Translational Research in Inflammation - U 1286 [INFINITE]
Néel, Antoine [Auteur]
Hôpital Foch [Suresnes]
Hôpital Ambroise Paré [AP-HP]
Centre Hospitalier Universitaire de Nantes = Nantes University Hospital [CHU Nantes]
Paris, Luc [Auteur]
Hôpital Ambroise Paré [AP-HP]
CHU Pitié-Salpêtrière [AP-HP]
Petit, Arnaud [Auteur]
CHU Trousseau [APHP]
Hôpital Ambroise Paré [AP-HP]
Rossignol, Julien [Auteur]
Hôpital Necker - Enfants Malades [AP-HP]
Hôpital Ambroise Paré [AP-HP]
Schleinitz, Nicolas [Auteur]
Hôpital Foch [Suresnes]
Hôpital de la Timone [CHU - APHM] [TIMONE]
Hôpital Ambroise Paré [AP-HP]
Soret-Dulphy, Juliette [Auteur]
Hôpital Ambroise Paré [AP-HP]
CIC Saint Louis [CIC-1427]
Terrier, Benjamin [Auteur]
Hôpital Ambroise Paré [AP-HP]
Terriou, Louis [Auteur]
Hôpital Foch [Suresnes]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Hôpital Ambroise Paré [AP-HP]
Viallard, Jean-François [Auteur]
Hôpital Foch [Suresnes]
Hôpital Ambroise Paré [AP-HP]
Centre Hospitalier Universitaire de Bordeaux [CHU Bordeaux]
Lefevre, Guillaume [Auteur]
Hôpital Foch [Suresnes]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Hôpital Ambroise Paré [AP-HP]
Centre Hospitalier Universitaire de Bordeaux [CHU Bordeaux]
Kahn, Jean-Emmannuel [Auteur]
Hôpital Foch [Suresnes]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Hôpital Ambroise Paré [AP-HP]
Lefevre, Guillaume [Auteur]

Journal title :

Orphanet J Rare Dis

Abbreviated title :

Orphanet J Rare Dis

Volume number :

18

Pages :

100

Publication date :

2023-05-01

ISSN :

1750-1172

English keyword(s) :

Hypereosinophilia
Hypereosinophilic syndromes
Recommendation
Management

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Eosinophilic-related clinical manifestations are protean and the underlying conditions underpinning eosinophilia are highly diverse. The etiological workup of unexplained eosinophilia/hypereosinophilia can be challenging, ...
Show more >Eosinophilic-related clinical manifestations are protean and the underlying conditions underpinning eosinophilia are highly diverse. The etiological workup of unexplained eosinophilia/hypereosinophilia can be challenging, and can lead sometimes to extensive, inappropriate, costly and/or invasive investigations. To date, guidelines for the etiological workup and management of eosinophilia are mainly issued by hematologists, and thus mostly cover the scope of clonal hypereosinophilic syndromes (HES). Here, thanks to an extensive literature review, and thanks to the joint work of a large panel of experts involving physicians from both adult and pediatric medicine and from various subspecialties (as well as a representative of a patients’ association representative), we provide recommendations for both the step-by step diagnostic workup of eosinophilia (whether unexplained or within specific contexts) as well as the management and follow-up of the full spectrum of eosinophilic disorders (including clonal, reactive, lymphocytic and idiopathic HES, as well as single-organ diseases). Didactic prescription summaries intended to facilitate the prescription of eosinophil-targeted drugs are also provided, as are practical diagnostic and therapeutic algorithms. Lastly, this set of recommendations also includes a summary intended for general practitioners, as well as an overview of the therapeutic patient education program set up by the French reference center for HES. Further updates will be mandatory as new validated information emerges.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Submission date :

2024-01-11T22:53:04Z
2024-03-22T14:07:06Z