Title :

Prevalence and determinants of fatigue in patients with IBD: a cross-sectional survey from the GETAID.

Author(s) :

Amiot, Aurelien [Auteur]
Hôpital Bicêtre [AP-HP, Le Kremlin-Bicêtre]
Chaibi, Sayma [Auteur]
Hôpital Henri Mondor
Bouhnik, Yoram [Auteur]
Hôpital Beaujon [AP-HP]
Serrero, Melanie [Auteur]
CHU Marseille
Filippi, Jerome [Auteur]
Centre Hospitalier Universitaire de Nice [CHU Nice]
Roblin, Xavier [Auteur]
Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] [CHU ST-E]
Bourrier, Anne [Auteur]
CHU Saint-Antoine [AP-HP]
Bouguen, Guillaume [Auteur]
Centre Hospitalier Universitaire [Rennes]
Franchimont, Denis [Auteur]
Hôpital Erasme [Bruxelles] [ULB]
Savoye, Guillaume [Auteur]
CHU Rouen
Buisson, Anthony [Auteur]
CHU Estaing [Clermont-Ferrand]
Louis, Edouard [Auteur]
Centre Hospitalier Universitaire de Liège [CHU-Liège]
Nancey, Stéphane [Auteur]
Hospices Civils de Lyon [HCL]
Abitbol, Vered [Auteur]
Hôpital Cochin [AP-HP]
Reimund, Jean-Marie [Auteur]
Dewit, Olivier [Auteur]
Cliniques Universitaires Saint-Luc [Bruxelles]
Vuitton, Lucine [Auteur]
Centre Hospitalier Régional Universitaire de Besançon [CHRU Besançon]
Mathieu, Nicolas [Auteur]
Centre Hospitalier Universitaire [CHU Grenoble] [CHUGA]
Peyrin-Biroulet, Laurent [Auteur]
Nutrition-Génétique et Exposition aux Risques Environnementaux [NGERE]
Gilletta, Cyrielle [Auteur]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Allez, Matthieu [Auteur]
Hopital Saint-Louis [AP-HP] [AP-HP]
Viennot, Stephanie [Auteur]
CHU Caen
Le Berre, Catherine [Auteur]
Centre Hospitalier Universitaire de Nantes = Nantes University Hospital [CHU Nantes]
Dib, Nina [Auteur]
Centre Hospitalier Universitaire d'Angers [CHU Angers]
Brixi, Hedia [Auteur]
Hôpital universitaire Robert Debré [Reims] [CHU Reims]
Painchart, Claire [Auteur]
Centre hospitalier [Valenciennes, Nord]
Plastaras, Laurianne [Auteur]
Hôpital pasteur [Colmar]
Altwegg, Romain [Auteur]
Hôpital Saint Eloi [CHRU Montpellier]
Fumery, Mathurin [Auteur]
CHU Amiens-Picardie
Caillo, Ludovic [Auteur]
Centre Hospitalier Universitaire de Nîmes [CHU Nîmes]
Laharie, David [Auteur]
Nachury, Maria [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]

Journal title :

Journal of Crohn's and Colitis

Abbreviated title :

J Crohns Colitis

Publication date :

2023-04-05

ISSN :

1876-4479

English keyword(s) :

Crohn's disease
ulcerative colitis
inflammatory bowel disease
disability
fatigue

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Background Fatigue is commonly reported by patients with inflammatory bowel disease [IBD], but the determinants of IBD-related fatigue have yet to be determined. Aims To identify the factors associated with fatigue ...
Show more >Background Fatigue is commonly reported by patients with inflammatory bowel disease [IBD], but the determinants of IBD-related fatigue have yet to be determined. Aims To identify the factors associated with fatigue in a large population of patients with IBD. Patients and Methods Fatigue and nine other IBD-related disability dimensions were assessed in a cohort of 1704 consecutive patients with IBD using the IBD-disk questionnaire in a cross-sectional survey of 42 French and Belgian centres. Fatigue and severe fatigue were defined as energy subscores >5 and >7, respectively. Determinants of fatigue were assessed using univariate and multivariate analyses (odds ratios [ORs] are provided with 95% confidence intervals). Results The prevalence rates of fatigue and severe fatigue were 54.1% and 37.1%, respectively. Both fatigue and severe fatigue were significantly higher in patients with active disease than in patients with inactive disease [64.9% vs 44.7% and 47.4% vs 28.6%, respectively; p < 0.001 for both comparisons]. In the multivariate analysis stratified by age, sex, type of IBD and IBD activity, fatigue was associated with age >40 years (OR = 0.71 [0.54–0.93]), female sex (OR = 1.48 [1.13–1.93]) and IBD-related sick leave (OR = 1.61 [1.19–2.16]), and joint pain (OR = 1.60 [1.17–2.18]), abdominal pain (OR = 1.78 [1.29–2.45]), regulating defecation (OR = 1.67 [1.20–2.32]), education and work (OR = 1.96 [1.40–2.75]), body image (OR = 1.38 [1.02–1.86]), sleep (OR = 3.60 [2.66–4.88]) and emotions (OR = 3.60 [2.66–4.88]) subscores >5. Conclusion Determinants of fatigue are not restricted to IBD-related factors but also include social factors, sleep and emotional disturbances, thus supporting a holistic approach to IBD patient care.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Submission date :

2024-01-11T23:05:23Z
2024-03-07T14:41:39Z
2024-04-23T11:22:18Z