Safety of hydrothermally treated kernels ...
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Article dans une revue scientifique: Article original
DOI :
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Title :
Safety of hydrothermally treated kernels from edible <i>Jatropha curcas</i> L. (Chuta) as a novel food pursuant to Regulation (EU) 2015/2283.
Author(s) :
Turck, Dominique [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Bohn, T. [Auteur]
European Food Safety Authority [EFSA]
Castenmiller, J. [Auteur]
De Henauw, S. [Auteur]
Hirsch-Ernst, K. I. [Auteur]
Maciuk, A. [Auteur]
Mangelsdorf, I. [Auteur]
Mcardle, H. J. [Auteur]
Naska, A. [Auteur]
Pelaez, C. [Auteur]
Pentieva, K. [Auteur]
Siani, A. [Auteur]
Thies, F. [Auteur]
Tsabouri, S. [Auteur]
Vinceti, M. [Auteur]
Cubadda, F. [Auteur]
Frenzel, T. [Auteur]
Heinonen, M. [Auteur]
Marchelli, R. [Auteur]
Neuhäuser-Berthold, M. [Auteur]
Poulsen, M. [Auteur]
Prieto Maradona, M. [Auteur]
Schlatter, J. R. [Auteur]
Van Loveren, H. [Auteur]
Colombo, P. [Auteur]
Knutsen, H. K. [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Bohn, T. [Auteur]
European Food Safety Authority [EFSA]
Castenmiller, J. [Auteur]
De Henauw, S. [Auteur]
Hirsch-Ernst, K. I. [Auteur]
Maciuk, A. [Auteur]
Mangelsdorf, I. [Auteur]
Mcardle, H. J. [Auteur]
Naska, A. [Auteur]
Pelaez, C. [Auteur]
Pentieva, K. [Auteur]
Siani, A. [Auteur]
Thies, F. [Auteur]
Tsabouri, S. [Auteur]
Vinceti, M. [Auteur]
Cubadda, F. [Auteur]
Frenzel, T. [Auteur]
Heinonen, M. [Auteur]
Marchelli, R. [Auteur]
Neuhäuser-Berthold, M. [Auteur]
Poulsen, M. [Auteur]
Prieto Maradona, M. [Auteur]
Schlatter, J. R. [Auteur]
Van Loveren, H. [Auteur]
Colombo, P. [Auteur]
Knutsen, H. K. [Auteur]
Journal title :
EFSA Journal
Abbreviated title :
EFSA J
Volume number :
20
Pages :
e06998
Publication date :
2022-02-04
ISSN :
1831-4732
English keyword(s) :
safety
novel food
anti-nutritional factors
hydrothermal treatment
phorbol esters
Chuta
edible Jatropha curcas kernels
novel food
anti-nutritional factors
hydrothermal treatment
phorbol esters
Chuta
edible Jatropha curcas kernels
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods andFood Allergens (NDA) was asked to deliver an opinion on hydrothermally treated kernels from edibleJatropha curcas(Chuta) as a ...
Show more >Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods andFood Allergens (NDA) was asked to deliver an opinion on hydrothermally treated kernels from edibleJatropha curcas(Chuta) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. AlthoughJatropha curcasis generally considered a toxic plant due to the presence of phorbol esters (PEs),edible varieties exist in Central America. The applicant has developed a breeding programme for anedible cultivar and proposes the kernels from this cultivar as an NF as whole kernels or fragmentsthereof to be used as a snack or as a food ingredient. Procedures are in place to avoid comminglingwith non-edible kernels, with the last steps being the analytical control of PEs concentrations in allproduced batches. The Panel considers that the production process of the NF is sufficiently describedand that the information provided on the composition of the NF is sufficient for its characterisation.Components of the NF were tested for genotoxicity applying the standardin vitrotest battery and nogenotoxic concerns have been identified. In a conservative scenario for exposure to PEs from the NF, itwas assumed that all kernels contain PEs at the level of detection of the analytical method. Whencomparing the estimated maximum exposure to PEs with a reference point from a subchronic study inpigs, a margin of exposure≥900 is obtained, which is considered sufficiently large. The presence ofanti-nutritional factors does not pose safety concerns as they are within the ranges found invegetables. The Panel concludes that the NF is safe under the proposed conditions of use.Show less >
Show more >Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods andFood Allergens (NDA) was asked to deliver an opinion on hydrothermally treated kernels from edibleJatropha curcas(Chuta) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. AlthoughJatropha curcasis generally considered a toxic plant due to the presence of phorbol esters (PEs),edible varieties exist in Central America. The applicant has developed a breeding programme for anedible cultivar and proposes the kernels from this cultivar as an NF as whole kernels or fragmentsthereof to be used as a snack or as a food ingredient. Procedures are in place to avoid comminglingwith non-edible kernels, with the last steps being the analytical control of PEs concentrations in allproduced batches. The Panel considers that the production process of the NF is sufficiently describedand that the information provided on the composition of the NF is sufficient for its characterisation.Components of the NF were tested for genotoxicity applying the standardin vitrotest battery and nogenotoxic concerns have been identified. In a conservative scenario for exposure to PEs from the NF, itwas assumed that all kernels contain PEs at the level of detection of the analytical method. Whencomparing the estimated maximum exposure to PEs with a reference point from a subchronic study inpigs, a margin of exposure≥900 is obtained, which is considered sufficiently large. The presence ofanti-nutritional factors does not pose safety concerns as they are within the ranges found invegetables. The Panel concludes that the NF is safe under the proposed conditions of use.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
Inserm
CHU Lille
Inserm
CHU Lille
Submission date :
2024-01-12T02:24:00Z
2024-03-08T13:46:56Z
2024-03-08T13:46:56Z
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