Thoracic involvement and imaging patterns ...
Type de document :
Article dans une revue scientifique: Article de synthèse/Review paper
PMID :
URL permanente :
Titre :
Thoracic involvement and imaging patterns in IgG4-related disease.
Auteur(s) :
Muller, Romain [Auteur]
Hôpital de la Timone [CHU - APHM] [TIMONE]
Habert, P. [Auteur]
Ebbo, M. [Auteur]
Graveleau, Julie [Auteur]
Centre hospitalier de Saint-Nazaire
Groh, Mathieu [Auteur]
Hôpital Foch [Suresnes]
Launay, David [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Audia, Sylvain [Auteur]
CHU Dijon
Pugnet, G. [Auteur]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Cohen, F. [Auteur]
CHU Pitié-Salpêtrière [AP-HP]
Perlat, A. [Auteur]
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Ponchaillou]
Benyamine, A. [Auteur]
Service de médecine interne [Hôpital Nord - APHM]
Bienvenu, B. [Auteur]
Hôpital Saint-Joseph [Marseille]
Gaigne, L. [Auteur]
Chanez, P. [Auteur]
Gaubert, J. Y. [Auteur]
Schleinitz, N. [Auteur]
Hôpital de la Timone [CHU - APHM] [TIMONE]
Habert, P. [Auteur]
Ebbo, M. [Auteur]
Graveleau, Julie [Auteur]
Centre hospitalier de Saint-Nazaire
Groh, Mathieu [Auteur]
Hôpital Foch [Suresnes]
Launay, David [Auteur]
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Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Audia, Sylvain [Auteur]
CHU Dijon
Pugnet, G. [Auteur]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Cohen, F. [Auteur]
CHU Pitié-Salpêtrière [AP-HP]
Perlat, A. [Auteur]
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Ponchaillou]
Benyamine, A. [Auteur]
Service de médecine interne [Hôpital Nord - APHM]
Bienvenu, B. [Auteur]
Hôpital Saint-Joseph [Marseille]
Gaigne, L. [Auteur]
Chanez, P. [Auteur]
Gaubert, J. Y. [Auteur]
Schleinitz, N. [Auteur]
Titre de la revue :
EUROPEAN RESPIRATORY REVIEW
Nom court de la revue :
Eur Respir Rev
Numéro :
30
Date de publication :
2021-10-08
ISSN :
1600-0617
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Objective Immunoglobulin G4-related disease (IgG4-RD) is a rare orphan disease. Lung, pleura, pericardium, mediastinum, aorta and lymph node involvement has been reported with variable frequency and mostly in Asian studies. ...
Lire la suite >Objective Immunoglobulin G4-related disease (IgG4-RD) is a rare orphan disease. Lung, pleura, pericardium, mediastinum, aorta and lymph node involvement has been reported with variable frequency and mostly in Asian studies. The objective of this study was to describe thoracic involvement assessed by high-resolution thoracic computed tomography (CT) in Caucasian patients with IgG4-RD. Methods Thoracic CT scans before treatment were retrospectively collected through the French case registry of IgG4-RD and a single tertiary referral centre. CT scans were reviewed by two experts in thoracic imagery blinded from clinical data. Results 48 IgG4-RD patients with thoracic involvement were analysed. All had American College of Rheumatology/European League Against Rheumatism classification scores ≥20 and comprehensive diagnostic criteria for IgG4-RD. CT scan findings showed heterogeneous lesions. Seven patterns were observed: peribronchovascular involvement (56%), lymph node enlargement (31%), nodular disease (25%), interstitial disease (25%), ground-glass opacities (10%), pleural disease (8%) and retromediastinal fibrosis (4%). In 37% of cases two or more patterns were associated. Asthma was significantly associated with peribronchovascular involvement (p=0.04). Among eight patients evaluated by CT scan before and after treatments, only two patients with interstitial disease displayed no improvement. Conclusion Thoracic involvement of IgG4-RD is heterogeneous and likely underestimated. The main thoracic CT scan patterns are peribronchovascular thickening and thoracic lymph nodes.Lire moins >
Lire la suite >Objective Immunoglobulin G4-related disease (IgG4-RD) is a rare orphan disease. Lung, pleura, pericardium, mediastinum, aorta and lymph node involvement has been reported with variable frequency and mostly in Asian studies. The objective of this study was to describe thoracic involvement assessed by high-resolution thoracic computed tomography (CT) in Caucasian patients with IgG4-RD. Methods Thoracic CT scans before treatment were retrospectively collected through the French case registry of IgG4-RD and a single tertiary referral centre. CT scans were reviewed by two experts in thoracic imagery blinded from clinical data. Results 48 IgG4-RD patients with thoracic involvement were analysed. All had American College of Rheumatology/European League Against Rheumatism classification scores ≥20 and comprehensive diagnostic criteria for IgG4-RD. CT scan findings showed heterogeneous lesions. Seven patterns were observed: peribronchovascular involvement (56%), lymph node enlargement (31%), nodular disease (25%), interstitial disease (25%), ground-glass opacities (10%), pleural disease (8%) and retromediastinal fibrosis (4%). In 37% of cases two or more patterns were associated. Asthma was significantly associated with peribronchovascular involvement (p=0.04). Among eight patients evaluated by CT scan before and after treatments, only two patients with interstitial disease displayed no improvement. Conclusion Thoracic involvement of IgG4-RD is heterogeneous and likely underestimated. The main thoracic CT scan patterns are peribronchovascular thickening and thoracic lymph nodes.Lire moins >
Langue :
Anglais
Comité de lecture :
Oui
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
Inserm
CHU Lille
Inserm
CHU Lille
Date de dépôt :
2024-01-12T05:57:34Z
2024-02-28T15:52:52Z
2024-02-28T15:52:52Z
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