Combating coxsackievirus B infections.
Document type :
Article dans une revue scientifique: Article de synthèse/Review paper
DOI :
PMID :
Permalink :
Title :
Combating coxsackievirus B infections.
Author(s) :
Alhazmi, Abdulaziz [Auteur]
Laboratoire de Virologie - ULR 3610 [Laboratoire de Virologie]
Nekoua, Magloire Pandoua [Auteur]
Laboratoire de virologie - ULR 3610
Mercier, Ambroise [Auteur]
Laboratoire de Virologie - ULR 3610 [Laboratoire de Virologie]
Vergez, Ines [Auteur]
Laboratoire de Virologie - ULR 3610 [Laboratoire de Virologie]
Sane, Famara [Auteur]
Laboratoire de virologie - ULR 3610
Alidjinou, Enagnon Kazali [Auteur]
Laboratoire de virologie - ULR 3610
Hober, Didier [Auteur]
Laboratoire de virologie - ULR 3610
Laboratoire de Virologie - ULR 3610 [Laboratoire de Virologie]
Nekoua, Magloire Pandoua [Auteur]
Laboratoire de virologie - ULR 3610
Mercier, Ambroise [Auteur]
Laboratoire de Virologie - ULR 3610 [Laboratoire de Virologie]
Vergez, Ines [Auteur]
Laboratoire de Virologie - ULR 3610 [Laboratoire de Virologie]
Sane, Famara [Auteur]

Laboratoire de virologie - ULR 3610
Alidjinou, Enagnon Kazali [Auteur]

Laboratoire de virologie - ULR 3610
Hober, Didier [Auteur]

Laboratoire de virologie - ULR 3610
Journal title :
Reviews in Medical Virology
Abbreviated title :
Rev Med Virol
Volume number :
33
Pages :
e2406
Publication date :
2022-11-15
ISSN :
1099-1654
HAL domain(s) :
Sciences du Vivant [q-bio]/Microbiologie et Parasitologie/Virologie
English abstract : [en]
Coxsackieviruses B (CVB) are small, non-enveloped, single-stranded RNA viruses belonging to the Enterovirus genus of the Picornaviridae family. They are common worldwide and cause a wide variety of human diseases ranging ...
Show more >Coxsackieviruses B (CVB) are small, non-enveloped, single-stranded RNA viruses belonging to the Enterovirus genus of the Picornaviridae family. They are common worldwide and cause a wide variety of human diseases ranging from those having relatively mild symptoms to severe acute and chronic pathologies such as cardiomyopathy and type 1 diabetes. The development of safe and effective strategies to combat these viruses remains a challenge. The present review outlines current approaches to control CVB infections and associated diseases. Various drugs targeting viral or host proteins involved in viral replication as well as vaccines have been developed and shown potential to prevent or combat CVB infections in vitro and in vivo in animal models. Repurposed drugs and alternative strategies targeting miRNAs or based on plant extracts and probiotics and their derivatives have also shown antiviral effects against CVB. In addition, clinical trials with vaccines and drugs are underway and offer hope for the prevention or treatment of CVB-induced diseases.Show less >
Show more >Coxsackieviruses B (CVB) are small, non-enveloped, single-stranded RNA viruses belonging to the Enterovirus genus of the Picornaviridae family. They are common worldwide and cause a wide variety of human diseases ranging from those having relatively mild symptoms to severe acute and chronic pathologies such as cardiomyopathy and type 1 diabetes. The development of safe and effective strategies to combat these viruses remains a challenge. The present review outlines current approaches to control CVB infections and associated diseases. Various drugs targeting viral or host proteins involved in viral replication as well as vaccines have been developed and shown potential to prevent or combat CVB infections in vitro and in vivo in animal models. Repurposed drugs and alternative strategies targeting miRNAs or based on plant extracts and probiotics and their derivatives have also shown antiviral effects against CVB. In addition, clinical trials with vaccines and drugs are underway and offer hope for the prevention or treatment of CVB-induced diseases.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
CHU Lille
CHU Lille
Collections :
Submission date :
2024-01-17T22:04:54Z
2024-02-09T10:38:44Z
2024-02-09T10:38:44Z