Combating coxsackievirus B infections.
Type de document :
Article dans une revue scientifique: Article de synthèse/Review paper
DOI :
PMID :
URL permanente :
Titre :
Combating coxsackievirus B infections.
Auteur(s) :
Alhazmi, Abdulaziz [Auteur]
Laboratoire de Virologie - ULR 3610 [Laboratoire de Virologie]
Nekoua, Magloire Pandoua [Auteur]
Laboratoire de virologie - ULR 3610
Mercier, Ambroise [Auteur]
Laboratoire de Virologie - ULR 3610 [Laboratoire de Virologie]
Vergez, Ines [Auteur]
Laboratoire de Virologie - ULR 3610 [Laboratoire de Virologie]
Sane, Famara [Auteur]
Laboratoire de virologie - ULR 3610
Alidjinou, Enagnon Kazali [Auteur]
Laboratoire de virologie - ULR 3610
Hober, Didier [Auteur]
Laboratoire de virologie - ULR 3610
Laboratoire de Virologie - ULR 3610 [Laboratoire de Virologie]
Nekoua, Magloire Pandoua [Auteur]
Laboratoire de virologie - ULR 3610
Mercier, Ambroise [Auteur]
Laboratoire de Virologie - ULR 3610 [Laboratoire de Virologie]
Vergez, Ines [Auteur]
Laboratoire de Virologie - ULR 3610 [Laboratoire de Virologie]
Sane, Famara [Auteur]

Laboratoire de virologie - ULR 3610
Alidjinou, Enagnon Kazali [Auteur]

Laboratoire de virologie - ULR 3610
Hober, Didier [Auteur]

Laboratoire de virologie - ULR 3610
Titre de la revue :
Reviews in Medical Virology
Nom court de la revue :
Rev Med Virol
Numéro :
33
Pagination :
e2406
Date de publication :
2022-11-15
ISSN :
1099-1654
Discipline(s) HAL :
Sciences du Vivant [q-bio]/Microbiologie et Parasitologie/Virologie
Résumé en anglais : [en]
Coxsackieviruses B (CVB) are small, non-enveloped, single-stranded RNA viruses belonging to the Enterovirus genus of the Picornaviridae family. They are common worldwide and cause a wide variety of human diseases ranging ...
Lire la suite >Coxsackieviruses B (CVB) are small, non-enveloped, single-stranded RNA viruses belonging to the Enterovirus genus of the Picornaviridae family. They are common worldwide and cause a wide variety of human diseases ranging from those having relatively mild symptoms to severe acute and chronic pathologies such as cardiomyopathy and type 1 diabetes. The development of safe and effective strategies to combat these viruses remains a challenge. The present review outlines current approaches to control CVB infections and associated diseases. Various drugs targeting viral or host proteins involved in viral replication as well as vaccines have been developed and shown potential to prevent or combat CVB infections in vitro and in vivo in animal models. Repurposed drugs and alternative strategies targeting miRNAs or based on plant extracts and probiotics and their derivatives have also shown antiviral effects against CVB. In addition, clinical trials with vaccines and drugs are underway and offer hope for the prevention or treatment of CVB-induced diseases.Lire moins >
Lire la suite >Coxsackieviruses B (CVB) are small, non-enveloped, single-stranded RNA viruses belonging to the Enterovirus genus of the Picornaviridae family. They are common worldwide and cause a wide variety of human diseases ranging from those having relatively mild symptoms to severe acute and chronic pathologies such as cardiomyopathy and type 1 diabetes. The development of safe and effective strategies to combat these viruses remains a challenge. The present review outlines current approaches to control CVB infections and associated diseases. Various drugs targeting viral or host proteins involved in viral replication as well as vaccines have been developed and shown potential to prevent or combat CVB infections in vitro and in vivo in animal models. Repurposed drugs and alternative strategies targeting miRNAs or based on plant extracts and probiotics and their derivatives have also shown antiviral effects against CVB. In addition, clinical trials with vaccines and drugs are underway and offer hope for the prevention or treatment of CVB-induced diseases.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
CHU Lille
CHU Lille
Collections :
Date de dépôt :
2024-01-17T22:04:54Z
2024-02-09T10:38:44Z
2024-02-09T10:38:44Z