Title :

High incidence of Epstein-Barr virus, cytomegalovirus, and human-herpes virus-6 reactivations in critically-ill patients with Covid-19.

Author(s) :

Simonnet, Arthur [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Engelmann, Ilka [Auteur]
Laboratoire de Virologie - ULR 3610 [Laboratoire de Virologie]
Moreau, Anne-Sophie [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
garcia, bruno [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Six, Sophie [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
El Kalioubie, Ahmed [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Robriquet, Laurent [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Hober, Didier [Auteur]
Laboratoire de virologie - ULR 3610
Jourdain, Mercedes [Auteur]
Recherche translationnelle sur le diabète (RTD) - U1190

Journal title :

Infectious Diseases Now

Abbreviated title :

Infect Dis Now

Volume number :

51

Pages :

296-299

Publication date :

2021-01-27

ISSN :

2666-9919

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Background Systemic reactivation of herpesviruses may occur in intensive care unit (ICU) patients and is associated with morbidity and mortality. Data on severe Coronavirus disease-19 (COVID-19) and concomitant reactivation ...
Show more >Background Systemic reactivation of herpesviruses may occur in intensive care unit (ICU) patients and is associated with morbidity and mortality. Data on severe Coronavirus disease-19 (COVID-19) and concomitant reactivation of herpesviruses are lacking. Methods We selected patients admitted to ICU for confirmed COVID-19 who underwent systematic testing for Epstein–Barr virus (EBV), cytomegalovirus (CMV) and human-herpes virus-6 (HHV-6) DNAemia while in the ICU. We retrospectively analysed frequency, timing, duration and co-occurrence of viral DNAemia. Results Thirty-four patients were included. Viremia with EBV, CMV, and HHV-6 was detected in 28 (82%), 5 (15%), and 7 (22%) patients, respectively. EBV reactivation occurred early after ICU admission and was associated with longer ICU length-of-stay. Conclusions While in the ICU, critically ill patients with COVID-19 are prone to develop reactivations due to various types of herpesviruses.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
CHU Lille

Collections :

• Laboratoire de virologie - ULR 3610
• Recherche translationnelle sur le diabète (RTD) - U1190

Submission date :

2024-01-17T22:18:40Z
2024-02-09T13:44:27Z