Title :

Cardiac autonomic modulation impairments in advanced breast cancer patients.

Author(s) :

Arab, C. [Auteur]
Vanderlei, L-C-M. [Auteur]
Da silva Paiva, L. [Auteur]
Fulghum, K-L. [Auteur]
Fristachi, C-E. [Auteur]
Nazario, A-C-P. [Auteur]
Elias, S. [Auteur]
Gebrim, L-H. [Auteur]
Ferreira Filho, C. [Auteur]
Gidron, Yori [Auteur]
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Ferreira, C. [Auteur]

Journal title :

Clinical Research in Cardiology

Volume number :

107

Pages :

p.924-936

Publication date :

2018-10

English keyword(s) :

Autonomic nervous system
Breast tumor
Cardiology
TNM classification.

HAL domain(s) :

Sciences cognitives

English abstract : [en]

Aim: To compare cardiac autonomic modulation in early- versus advanced-stage breast cancer patients before any type of cancer treatment and investigate associated factors. Methods and results: This cross-sectional study ...
Show more >Aim: To compare cardiac autonomic modulation in early- versus advanced-stage breast cancer patients before any type of cancer treatment and investigate associated factors. Methods and results: This cross-sectional study included women (30-69 years old) with primary diagnosis of breast cancer and women with benign breast tumors. We evaluated cardiac modulation by heart rate variability and assessed factors of anxiety, depression, physical activity, and other relevant medical variables. Patients were divided into three groups based on TNM staging of cancer severity: early-stage cancer (n = 42), advanced-stage cancer (n = 37), or benign breast tumors to serve as a control (n = 37). We analyzed heart rate variability in time and frequency domains. The advanced-stage cancer group had lower vagal modulation than early-stage and benign groups; also, the advance-stage group had lower overall heart rate variability when compared to benign conditions. Heart rate variability was influenced by age, menopausal status, and BMI. Conclusions: Heart rate variability seems to be a promising, non-invasive tool for early diagnosis of autonomic dysfunction in breast cancer and detection of cardiovascular impairments at cancer diagnosis. Cardiac autonomic modulation is inversely associated with breast cancer staging.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
CNRS
CHU Lille

Collections :

• Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193

Research team(s) :

Équipe Dynamique Émotionnelle et Pathologies (DEEP)

Submission date :

2024-01-18T11:14:31Z
2024-01-26T09:35:21Z