Title :

Safety and efficacy of thermal ablation (radiofrequency and laser): should we treat all types of thyroid nodules?

Author(s) :

Ben Hamou, Adrien [Auteur]
Service Endocrinologie, diabétologie, maladies métaboliques et nutrition [LILLE - Endocrino]
Ghanassia, Edouard [Auteur]
Service Endocrinologie, diabétologie, maladies métaboliques et nutrition [LILLE - Endocrino]
Stephanie, Espiard [Auteur]
Service Endocrinologie, diabétologie, maladies métaboliques et nutrition [LILLE - Endocrino]
Abi Rached, Henry [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Jannin, Arnaud [Auteur]
Service Endocrinologie, diabétologie, maladies métaboliques et nutrition [LILLE - Endocrino]
Correas, Jean-Michel [Auteur]
Service de radiologie [CHU Necker]
Do Cao, Christine [Auteur]
Service Endocrinologie, diabétologie, maladies métaboliques et nutrition [LILLE - Endocrino]
Kyheng, Maéva [Auteur]
Santé Publique : épidémiologie et qualité des soins [EA 2694]
Vantyghem, Marie-Christine [Auteur]
Service Endocrinologie, diabétologie, maladies métaboliques et nutrition [LILLE - Endocrino]
Recherche translationnelle sur le diabète (RTD) - U1190
Monpeyssen, Hervé [Auteur]
Hôpital Américain de Paris

Journal title :

International Journal of Hyperthermia

Abbreviated title :

Int J Hyperthermia

Volume number :

36

Pages :

666-676

Publisher :

Taylor & Francis

Publication date :

2019-07-18

ISSN :

1464-5157

English keyword(s) :

Benign thyroid nodule
image-guided ablation
radiofrequency ablation
laser ablation

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Background: Thermal ablation is a minimally invasive technique that is gradually acknowledged as an effective alternative to surgery to treat thyroid nodules. Two main techniques have been described: radiofrequency (RFA) ...
Show more >Background: Thermal ablation is a minimally invasive technique that is gradually acknowledged as an effective alternative to surgery to treat thyroid nodules. Two main techniques have been described: radiofrequency (RFA) and laser ablation. Objective: To evaluate the safety and efficacy of the two main techniques (RFA and laser ablation) for the treatment of benign thyroid nodules. Patients: This bicentric retrospective study included 166 consecutive patients, who received clinical, biological and ultrasound evaluations for thyroid nodules, from October 2013 to November 2017. Methods: One of the two techniques was proposed if a nodule was proven to be benign after fine needle aspiration cytology or micro-biopsy. Adverse events and outcomes (symptoms, nodule reduction) were assessed at 6 weeks and 6, 12, and 18 months after treatment. Results: One hundred and eighty-nine nodules (mean size 17.5 ± 16.9 mL, 86.1% palpable) were treated by RFA (n = 108 (57.1%)) or laser ablation (n = 81 (42.9%)) in 166 patients (80.1% women, mean age 51.7 years). Two cases of transient recurrent laryngeal nerve palsy, one hematoma, and two successfully drained abscesses (5/166 = 3%) were observed. Clinical symptoms improved significantly in the two groups (anterior cervical discomfort –83.6%, esthetic complaints –84.9% and dysphagia –86.4%). Nodule volume (mL) decreased significantly (baseline vs. 18 months) from 20.4 ± 18.6 to 5.8 ± 6.6 (−75%) in the RFA, and from 13.6 ± 13.3 to 3.4 ± 4.1 (−83.9%) in the laser ablation groups. Conclusions: Transient but potentially serious adverse events were reported in 3% of patients. A significant volumetric reduction was achieved with both techniques, regardless of nodule’s characteristics, at 18 months.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Recherche translationnelle sur le diabète (RTD) - U1190

Submission date :

2024-01-19T23:48:55Z
2024-10-04T13:35:31Z