Title :

Association between cardiopulmonary resuscitation duration and survival after out-of-hospital cardiac arrest according: a first nationwide study in France.

Author(s) :

Jaeger, Deborah [Auteur]
Centre Hospitalier Régional Universitaire de Nancy [CHRU Nancy]
University of Minnesota Medical School
Lafrance, Martin [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Canon, Valentine [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Kosmopoulos, Marinos [Auteur]
University of Minnesota Medical School
Gaisendrees, Christopher [Auteur]
University of Minnesota Medical School
University Hospital of Cologne [Cologne]
Debaty, Guillaume [Auteur]
Centre Hospitalier Universitaire [CHU Grenoble] [CHUGA]
Yannopoulos, Demetri [Auteur]
University of Minnesota Medical School
Hubert, Hervé [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Chouihed, Tahar [Auteur]
Centre Hospitalier Régional Universitaire de Nancy [CHRU Nancy]

Journal title :

Internal and Emergency Medicine

Abbreviated title :

Intern Emerg Med

Publication date :

2023-11-01

ISSN :

1970-9366

English abstract : [en]

Objective Determining whether to pursue or terminate resuscitation efforts remains one of the biggest challenges of cardiopulmonary resuscitation (CPR). No ideal cut-off duration has been recommended and the association ...
Show more >Objective Determining whether to pursue or terminate resuscitation efforts remains one of the biggest challenges of cardiopulmonary resuscitation (CPR). No ideal cut-off duration has been recommended and the association between CPR duration and survival is still unclear for out-of-hospital cardiac arrest (OHCA). The aim of this study was to assess the association between CPR duration and 30-day survival after OHCA with favorable neurological outcomes according to initial rhythm. Methods This was an observational, retrospective analysis of the French national multicentric registry on cardiac arrest, RéAC. The primary endpoint was neurologically intact 30-day survival according to initial rhythm. Results 20,628 patients were included. For non-shockable rhythms, the dynamic probability of 30-day survival with a Cerebral Performance Category (CPC) of 1 or 2 was less than 1% after 25 min of CPR. CPR duration over 10 min was not associated with 30-day survival with CPC of 1 or 2 (adjusted OR: 1.67; CI 95% 0.95–2.94). For shockable rhythms, the dynamic probability of 30-day survival with a CPC score of 1 or 2, was less than 1% after 54 min of CPR. CPR duration of 21–25 min was still associated with 30-day survival and 30-day survival with a CPC of 1 or 2 (adjusted OR: 2.77; CI 95% 2.16–3.57 and adjusted OR: 1.82; CI 95% 1.06–3.13, respectively). Conclusions Survival decreased rapidly with increasing CPR duration, especially for non-shockable rhythms. Pursuing CPR after 25 min may be futile for patients presenting a non-shockable rhythm. On the other hand, shockable rhythms might benefit from prolonged CPR.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
CHU Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Submission date :

2024-01-20T22:05:06Z
2024-04-10T08:39:54Z