Titre :

Neurodevelopment and healthcare utilisation at age 5-6 years in bronchopulmonary dysplasia: an EPIPAGE-2 cohort study.

Auteur(s) :

Tréluyer, Ludovic [Auteur]
Centre for Research in Epidemiology and Statistics | Centre de Recherche Épidémiologie et Statistiques [CRESS (U1153 / UMR_A 1125)]
Institut Cochin [IC UM3 (UMR 8104 / U1016)]
Nuytten, Alexandra [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Guellec, Isabelle [Auteur]
Centre Hospitalier Universitaire de Nice [CHU Nice]
Jarreau, Pierre-Henri [Auteur]
Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité [CRESS (U1153 / UMR_A_1125 / UMR_S_1153)]
Institut Cochin [IC UM3 (UMR 8104 / U1016)]
Benhammou, Valérie [Auteur]
Centre for Research in Epidemiology and Statistics | Centre de Recherche Épidémiologie et Statistiques [CRESS (U1153 / UMR_A 1125)]
Cambonie, Gilles [Auteur]
Centre Hospitalier Régional Universitaire [Montpellier] [CHRU Montpellier]
Truffert, Patrick [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Marchand-Martin, Laetitia [Auteur]
Centre for Research in Epidemiology and Statistics | Centre de Recherche Épidémiologie et Statistiques [CRESS (U1153 / UMR_A 1125)]
Ancel, Pierre-Yves [Auteur]
CIC - Mère Enfant Necker Cochin Paris Centre [CIC 1419]
Centre for Research in Epidemiology and Statistics | Centre de Recherche Épidémiologie et Statistiques [CRESS (U1153 / UMR_A 1125)]
Torchin, Héloïse [Auteur]
Centre for Research in Epidemiology and Statistics | Centre de Recherche Épidémiologie et Statistiques [CRESS (U1153 / UMR_A 1125)]
Institut Cochin [IC UM3 (UMR 8104 / U1016)]

Titre de la revue :

Archives of disease in childhood. Fetal and neonatal edition

Nom court de la revue :

Arch Dis Child Fetal Neonatal Ed

Date de publication :

2023-06-27

ISSN :

1468-2052

Mot(s)-clé(s) en anglais :

neonatology
child development
epidemiology

Résumé en anglais : [en]

Objective We aimed to study neurodevelopmental outcomes and healthcare utilisation at age 5–6 years in very preterm children with bronchopulmonary dysplasia (BPD). Design Prospective and national population-based ...
Lire la suite >Objective We aimed to study neurodevelopmental outcomes and healthcare utilisation at age 5–6 years in very preterm children with bronchopulmonary dysplasia (BPD). Design Prospective and national population-based study. Setting All the neonatal units in 25 French regions (21 of the 22 metropolitan regions and 4 overseas regions). Patients Children born before 32 weeks’ gestation in 2011. Interventions Blind, comprehensive and standardised assessment by trained neuropsychologists and paediatricians at age 5–6 years. Main outcome measures Overall neurodevelopmental disabilities, behavioural difficulties, developmental coordination disorders, full-scale IQ, cerebral palsy, social interaction disorders, rehospitalisation in the previous 12 months and detailed developmental support. Results Of the 3186 children included, 413 (11.7%) had BPD. The median gestational age of children with BPD was 27 weeks (IQR 26.0–28.0) and without BPD was 30 weeks (28.0–31.0). At age 5–6 years, 3150 children were alive; 1914 (60.8%) had a complete assessment. BPD was strongly associated with mild, moderate and severe overall neurodevelopmental disabilities (OR 1.49, 95% CI 1.05 to 2.20; 2.20, 1.41 to 3.42 and 2.71, 1.67 to 4.40). BPD was associated with developmental coordination disorders, behavioural difficulties, lower IQ score as well as rehospitalisation in the last 12 months and developmental support. The association between BPD and cerebral palsy was statistically significant before adjustment but not in adjusted analyses. Conclusions BPD was strongly and independently associated with many neurodevelopmental disabilities. Improving medical and neurodevelopmental management of BPD in very preterm children should be a priority to reduce its long-term consequences.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

Université de Lille
CHU Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Date de dépôt :

2024-01-20T22:13:02Z
2024-04-09T12:02:36Z