Title :

Treatment of noninfectious intermediate uveitis, posterior uveitis, or panuveitis

Author(s) :

Couret, C. [Auteur]
Ducloyer, J.-B. [Auteur]
Touhami, S. [Auteur]
Angioi-Duprez, K. [Auteur]
Rougier, M.-B. [Auteur]
Labalette, Pierre [Auteur]
Titah, C. [Auteur]
Cochereau, I. [Auteur]
Kodjikian, L. [Auteur]
Mura, F. [Auteur]
Chiquet, C. [Auteur]
Weber, M. [Auteur]
Bodaghi, B. [Auteur]

Journal title :

Journal francais d'ophtalmologie

Abbreviated title :

J Fr Ophtalmol

Publication date :

2019-12-06

ISSN :

1773-0597

English keyword(s) :

Uveitis
Pariuveitis
Steroid treatment
Biologic treatment
Immunosuppressant
Treatment
Intermediate uveitis
Posterior uveitis
Non-infectious uveitis

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Controlling long-term inflammation during non-infectious intermediate, posterior or panuveitis while limiting side effects remains challenging. There is no standardized pre-therapeutic evaluation providing diagnostic ...
Show more >Controlling long-term inflammation during non-infectious intermediate, posterior or panuveitis while limiting side effects remains challenging. There is no standardized pre-therapeutic evaluation providing diagnostic certainty, but some simple tests allow us to identifiy the main etiologies. The ophthalmologist identifies the type of uveitis, and the internist completes the investigations according to the ophthalmologist's findings. Fundus photographs, optical coherence tomography, and fluorescein and indocyanine green angiography should be considered during diagnosis and follow-up. Ocular complications of uveitis are numerous. They require close monitoring and specific medical and sometimes surgical management. The growing number of available drugs makes it possible to optimize the management of these conditions with varied etiologies and presentations. Currently, systemic corticosteroids remain the mainstay of therapy, and other alternatives are considered in the case of poor tolerance, steroid resistance or dependence. The choice of a systemic, periocular or intravitreal treatment depends on several factors: chronicity or recurrence of uveitis, duration, bilaterality, association with a systemic inflammatory disease, the presence of contraindications to certain treatments, and also socioeconomic constraints. It is of the utmost importance to find the best compromise allowing tight control of ocular inflammation by means of adapted systemic and/or local treatment while avoiding the main complications.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Inserm
Université de Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Submission date :

2024-01-30T10:28:27Z