Title :

Association Between Comorbidities and Quality of Life in Psoriatic Arthritis: Results from a Multicentric Cross-sectional Study

Author(s) :

Bavière, Wallis [Auteur]
Deprez, Xavier [Auteur]
Houvenagel, Eric [Auteur]
Hôpital Saint Philibert [Lomme]
Philippe, Peggy [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Deken, Valerie [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Flipo, Rene-Marc [Auteur]
Hôpital Roger Salengro [Lille]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Paccou, Julien [Auteur]
Marrow Adiposity & Bone Lab - Adiposité Médullaire et Os - ULR 4490 [MABLab]
Université de Lille

Journal title :

Journal of Rheumatology

Pages :

369-376

Publisher :

Journal of Rheumatology Publishing Company Limited

Publication date :

2020-03-15

ISSN :

0315-162X

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Objective. In psoriatic arthritis (PsA), comorbidities add to the burden of disease, which may lead to poorer quality of life. The purpose of this study was to evaluate the relationship between comorbidities and quality ...
Show more >Objective. In psoriatic arthritis (PsA), comorbidities add to the burden of disease, which may lead to poorer quality of life. The purpose of this study was to evaluate the relationship between comorbidities and quality of life (QOL). Methods. Patients from a multicentric, cross-sectional study on comorbidities in PsA were included in the analysis. Data on comorbidities were collected and were subsequently used to compute the modified Rheumatic Disease Comorbidity Index (mRDCI). The Medical Outcomes Study Short Form-36 questionnaire physical (PCS) and mental component summary (MCS) scales were used to assess QOL. Results. In total, 124 recruited patients fulfilled the ClASsification for Psoriatic ARthritis criteria (CASPAR): 62.1% were male; mean age and mean disease duration were 52.6 ± 12.6 years and 11.3 ± 9.6 years, respectively. The number of comorbid conditions was 2.0 ± 1.3, with 30.6% of the sample having currently or a history of 3 or more comorbidities. In the multivariate linear regression analysis, only anxiety remained significantly related to mental health (p < 0.0001). Anxiety alone accounted for 28.7% of the variance in MCS scores. Moreover, MCS was also significantly associated with the mRDCI score, which explained 4.9% of the variance in MCS [β = −1.56 (standard error 0.64), R 2 = 0.049, p = 0.0167]. In contrast, PCS was not significantly associated either with type or number of comorbidities. Conclusion. In this study, the type of comorbidity appeared to have a greater effect than the number of comorbidities. Indeed, anxiety in PsA was independently associated with QOL and would thus be an important factor to take into account in daily clinical practice.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Collections :

• Marrow Adiposity & Bone Lab (MABLab) - ULR 4490

Source :

Harvested from HAL