Title :

Effect of caloric restriction with or without physical activity on body composition and epicardial fat in type 2 diabetic patients: A pilot randomized controlled trial.

Author(s) :

Leroux-Stewart, Josée [Auteur]
Institut de Recherches Cliniques de Montréal [IRCM]
Elisha, Belinda [Auteur]
Institut de Recherches Cliniques de Montréal [IRCM]
Tagougui, Sémah [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369
Suppère, Corinne [Auteur]
Institut de Recherches Cliniques de Montréal [IRCM]
Bernard, Sophie [Auteur]
Institut de Recherches Cliniques de Montréal [IRCM]
Mircescu, Hortensia [Auteur]
Institut de Recherches Cliniques de Montréal [IRCM]
Desjardin, Katherine [Auteur]
Institut de Recherches Cliniques de Montréal [IRCM]
Messier, Virginie [Auteur]
Institut de Recherches Cliniques de Montréal [IRCM]
Iacobellis, Gianluca [Auteur]
University of Miami Leonard M. Miller School of Medicine [UMMSM]
Rabasa-Lhoret, Rémi [Auteur]
Institut de Recherches Cliniques de Montréal [IRCM]

Journal title :

Nutrition, metabolism, and cardiovascular diseases : NMCD

Abbreviated title :

Nutr Metab Cardiovasc Dis

Volume number :

31

Pages :

921-929

Publisher :

Elsevier

Publication date :

2021-03-10

ISSN :

1590-3729

English keyword(s) :

Adiposity
Adult
Aged
Body Composition
Caloric Restriction
Cardiometabolic Risk Factors
Diabetes Mellitus, Type 2
Exercise Therapy
Female
Humans
Male
Middle Aged
Pericardium
Pilot Projects
Quebec
Time Factors
Treatment Outcome
Cardiovascular risk factors
Energy restriction
Epicardial fat thickness
Structured exercise
Total fat mass
Type 2 diabetes

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

There is debate over the independent and combined effects of caloric restriction (CR) and physical activity (PA) on reduction in fat mass and in epicardial fat thickness. We compared the impact of a similar energy deficit ...
Show more >There is debate over the independent and combined effects of caloric restriction (CR) and physical activity (PA) on reduction in fat mass and in epicardial fat thickness. We compared the impact of a similar energy deficit prescription by CR or by CR combined with PA on total fat mass, epicardial fat thickness, and cardiometabolic profile in individuals with type 2 diabetes. In this 16-week randomized controlled study, 73 individuals were randomly enrolled to receive: 1) a monthly motivational phone call (Control), 2) a caloric deficit of -700 kilocalories/day (CR), or 3) a caloric deficit of -500 kilocalories/day combined with a PA program of -200 kilocalories/day (CR&PA). Total fat mass, epicardial fat, and cardiometabolic profile were measured at baseline and after 16 weeks. While comparable weight loss occurred in both intervention groups (-3.9 ± 3.5 kg [CR], -5.1 ± 4.7 kg [CR&PA], -0.2 ± 2.9 kg [Control]), changes in total fat mass were significantly different between all groups (-2.4 ± 2.9 kg [CR], -4.5 ± 3.4 kg [CR&PA], +0.1 ± 2.1 kg [Control]; p < 0.05) as well as epicardial fat thickness (-0.4 ± 1.6 mm [CR], -1.4 ± 1.4 mm [CR&PA], +1.1 ± 1.3 mm [Control]; p < 0.05). There were no significant differences in trends for cardiometabolic parameters improvement between groups. For a similar energy deficit prescription and comparable weight loss, the combination of CR&PA provides a greater reduction in fat mass and epicardial fat thickness than CR alone in individuals with comparable weight loss and with a similar energy deficit prescription. These results, however, do not translate into significant improvements in cardiometabolic profiles.Show less >

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Univ. Artois
Univ. Littoral Côte d’Opale

Collections :

• Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369

Research team(s) :

Responsabilité des acteurs du sport et de l’éducation

Submission date :

2024-04-04T23:42:25Z
2024-04-10T07:28:56Z