Title :

Comparison of two carbohydrate intake strategies to improve glucose control during exercise in adolescents and adults with type 1 diabetes.

Author(s) :

Goulet-Gélinas, Lucas [Auteur]
Université de Montréal [UdeM]
Saade, Marie-Béatrice [Auteur]
Institut de Recherches Cliniques de Montréal [IRCM]
Suppère, Corinne [Auteur]
Institut de Recherches Cliniques de Montréal [IRCM]
Fortin, Andréanne [Auteur]
Institut de Recherches Cliniques de Montréal [IRCM]
Messier, Virginie [Auteur]
Institut de Recherches Cliniques de Montréal [IRCM]
Taleb, Nadine [Auteur]
Institut de Recherches Cliniques de Montréal [IRCM]
Tagougui, Sémah [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369
Shohoudi, Azadeh [Auteur]
Legault, Laurent [Auteur]
McGill University = Université McGill [Montréal, Canada]
Henderson, Mélanie [Auteur]
Centre de recherche du CHU Sainte-Justine / Research Center of the Sainte-Justine University Hospital [Montreal, Canada]
Rabasa-Lhoret, Rémi [Auteur]
Institut de Recherches Cliniques de Montréal [IRCM]

Journal title :

Nutrition, metabolism, and cardiovascular diseases : NMCD

Abbreviated title :

Nutr Metab Cardiovasc Dis

Volume number :

31

Pages :

1238-1246

Publisher :

Elsevier

Publication date :

2021-04-09

ISSN :

1590-3729

English keyword(s) :

Adolescent
Adult
Age Factors
Biomarkers
Blood Glucose
Cross-Over Studies
Diabetes Mellitus, Type 1
Dietary Carbohydrates
Exercise
Female
Glycated Hemoglobin
Glycemic Control
Humans
Hypoglycemia
Male
Middle Aged
Quebec
Time Factors
Treatment Outcome
Carbohydrate intake
Glycemic control & hypoglycemia
Physical activity
Type 1 diabetes

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

During aerobic physical activity (PA), hypoglycemia is common in people with type 1 diabetes (T1D). Few studies have compared the effectiveness of different carbohydrate (CHO) intake strategies to prevent PA-induced ...
Show more >During aerobic physical activity (PA), hypoglycemia is common in people with type 1 diabetes (T1D). Few studies have compared the effectiveness of different carbohydrate (CHO) intake strategies to prevent PA-induced hypoglycemia. Our objective was to compare the efficacy of two CHO intake strategies, same total amount but different CHO intake timing, to maintain glucose levels in the target range (4.0-10.0 mmol/L) during PA in people with T1D. An open-label, randomized, crossover study in 33 participants (21 adults; 12 adolescents). Participants practiced 60 min PA sessions (ergocyle) at 60% VO 3.5 h after lunch comparing an intake of 0.5 g of CHO per kg of body weight applied in a pre-PA single CHO intake (SCI) or in a distributed CHO intake (DCI) before and during PA. The percentage of time spent in glucose level target range during PA was not different between the two strategies (SCI: 75 ± 35%; DCI: 87 ± 26%; P = 0.12). Hypoglycemia (<4.0 mmol/L) occurred in 4 participants (12%) with SCI compared to 6 participants (18%) with DCI (P = 0.42). The SCI strategy led to a higher increase (P = 0.01) and variability of glucose levels (P = 0.04) compared with DCI. In people living with T1D, for a 60 min moderate aerobic PA in the post-absorptive condition, a 0.5 g/kg CHO intake helped most participants maintain acceptable glycemic control with both strategies. No clinically significant difference was observed between the SCI and DCI strategies.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Univ. Artois
Univ. Littoral Côte d’Opale

Collections :

• Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369

Research team(s) :

Activité Physique, Muscle, Santé (APMS)

Submission date :

2024-04-04T23:44:24Z
2024-04-10T06:49:16Z
2024-04-10T06:51:58Z