Titre :

Statistical approach of chemistry and topography effect on human osteoblast adhesion

Auteur(s) :

Giljean, Sylvain [Auteur]
Institut de Science des Matériaux de Mulhouse [IS2M]
Ponche, Arnaud [Auteur]
Institut de Science des Matériaux de Mulhouse [IS2M]
Bigerelle, Maxence [Auteur]
Roberval [Roberval]
Laboratoire de Métallurgie Physique et Génie des Matériaux [LMPGM]
Anselme, Karine [Auteur]
Laboratoire de Recherche sur les Biomatériaux et les Biotechnologies [LR2B]
Institut de Science des Matériaux de Mulhouse [IS2M]

Titre de la revue :

Journal of Biomedical Materials Research Part A

Pagination :

1111-1123

Éditeur :

Wiley

Date de publication :

2010-09

ISSN :

1549-3296

Mot(s)-clé(s) en anglais :

surface chemistry
topography
titanium
stainless steel
adhesion
osteoblast

Discipline(s) HAL :

Sciences du Vivant [q-bio]/Ingénierie biomédicale/Biomatériaux
Sciences du Vivant [q-bio]/Biologie cellulaire
Statistiques [stat]/Applications [stat.AP]

Résumé en anglais : [en]

Our objective in this work was to determine statistically the relative influence of surface topography and surface chemistry of metallic substrates on long‐term adhesion of human bone cell quantified by the adhesion power ...
Lire la suite >Our objective in this work was to determine statistically the relative influence of surface topography and surface chemistry of metallic substrates on long‐term adhesion of human bone cell quantified by the adhesion power (AP). Pure titanium, titanium alloy, and stainless steel substrates were processed with electro‐erosion, sandblasting, or polishing giving various morphologies and amplitudes. The surface chemistry was characterized by X‐ray photoelectron spectroscopy (XPS) associated with an extensive analysis of surface topography. The statistical analysis demonstrated that the effect on AP of the material composition was not significant. More, no correlation was found between AP and the surface element concentrations determined by XPS demonstrating that the surface chemistry was not an influencing parameter for long‐term adhesion. In the same way, the roughness amplitude, independently of the process, had no influence on AP, meaning that roughness amplitude is not an intrinsic parameter of long‐term adhesion. On the contrary, the elaboration process alone had a significant effect on AP. For a same surface elaboration process, the number of inflexion points, or G parameter, was the most pertinent roughness parameter for describing the topography influence on long‐term adhesion. Thus, more the inflexion points, more the discontinuities, higher the long‐term adhesion. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2010Lire moins >

Langue :

Anglais

Comité de lecture :

Oui

Audience :

Non spécifiée

Vulgarisation :

Non

Collections :

• Marrow Adiposity & Bone Lab (MABLab) - ULR 4490

Source :

Harvested from HAL