Cocktails of endocrine disruptors in the ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Cocktails of endocrine disruptors in the different diets of French consumers.
Auteur(s) :
Dervilly, Gaud [Auteur]
Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement [INRAE]
École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique [ONIRIS]
Laboratoire d'étude des Résidus et Contaminants dans les Aliments [LABERCA]
Bourdeau, Manon [Auteur]
École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique [ONIRIS]
Laboratoire d'étude des Résidus et Contaminants dans les Aliments [LABERCA]
Pruvost-Couvreur, Manon [Auteur]
École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique [ONIRIS]
Laboratoire d'étude des Résidus et Contaminants dans les Aliments [LABERCA]
Severin, Isabelle [Auteur]
Equipe NuTox (LNC - U1231) [NUTOX]
Platel, Anne [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Chagnon, M. C. [Auteur]
Equipe NuTox (LNC - U1231) [NUTOX]
Nesslany, Fabrice [Auteur]
Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
Le Bizec, Bruno [Auteur]
Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement [INRAE]
École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique [ONIRIS]
Laboratoire d'étude des Résidus et Contaminants dans les Aliments [LABERCA]
Moche, Hélène [Auteur]
Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement [INRAE]
École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique [ONIRIS]
Laboratoire d'étude des Résidus et Contaminants dans les Aliments [LABERCA]
Bourdeau, Manon [Auteur]
École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique [ONIRIS]
Laboratoire d'étude des Résidus et Contaminants dans les Aliments [LABERCA]
Pruvost-Couvreur, Manon [Auteur]
École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique [ONIRIS]
Laboratoire d'étude des Résidus et Contaminants dans les Aliments [LABERCA]
Severin, Isabelle [Auteur]
Equipe NuTox (LNC - U1231) [NUTOX]
Platel, Anne [Auteur]
![refId](/themes/Mirage2//images/idref.png)
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Chagnon, M. C. [Auteur]
Equipe NuTox (LNC - U1231) [NUTOX]
Nesslany, Fabrice [Auteur]
![refId](/themes/Mirage2//images/idref.png)
Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
Le Bizec, Bruno [Auteur]
Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement [INRAE]
École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique [ONIRIS]
Laboratoire d'étude des Résidus et Contaminants dans les Aliments [LABERCA]
Moche, Hélène [Auteur]
Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
Titre de la revue :
Environ Int
Nom court de la revue :
Environ Int
Numéro :
183
Pagination :
108408
Éditeur :
Elsevier
Date de publication :
2024-01-20
ISSN :
1873-6750
Mot(s)-clé(s) en anglais :
Dietary patterns
Endocrine disruptors
Mixtures
Co-exposure assessment
Sparse and Unique Non-negative Matrix
Factorization
Endocrine disruptors
Mixtures
Co-exposure assessment
Sparse and Unique Non-negative Matrix
Factorization
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
With a view to identifying main endocrine disruptors (ED) mixtures to which French consumers are exposed through food, their main diets were modelled using an adapted dimension reduction method. Seven specific diets could ...
Lire la suite >With a view to identifying main endocrine disruptors (ED) mixtures to which French consumers are exposed through food, their main diets were modelled using an adapted dimension reduction method. Seven specific diets could be modelled for adults while only one overall diet was considered for children aged 3–17 years. The knowledge of the contamination levels of 78 known or suspected endocrine disrupting compounds in the foods constituting these diets, collected in the frame of the second French Total Diet Study, made it possible to explore the mixtures of EDs to which consumers are exposed. We have thus shown that the ED substances most present in mass concentration are comparable for the whole population, whatever the diet considered. However, a second approach made it possible to highlight, for a given diet, the substances whose exposure is statistically higher than in the diet of the general population. Thus, significantly different ED mixtures could be established for each diet. For example, diets with a high proportion of animal-based foods induce significantly higher exposures to some persistent organic pollutants (e.g., PCDD/F, brominated flame retardants), whereas these exposures are lower for Mediterranean-type diet. On the other hand, the latter, richer in fruits and vegetables, is the one for which pesticides represent a specific signature.These results now pave the way for studying the specific effects of these cocktails of endocrine disruptors, each of which is representative of a type of chronic exposure linked to specific diets.Lire moins >
Lire la suite >With a view to identifying main endocrine disruptors (ED) mixtures to which French consumers are exposed through food, their main diets were modelled using an adapted dimension reduction method. Seven specific diets could be modelled for adults while only one overall diet was considered for children aged 3–17 years. The knowledge of the contamination levels of 78 known or suspected endocrine disrupting compounds in the foods constituting these diets, collected in the frame of the second French Total Diet Study, made it possible to explore the mixtures of EDs to which consumers are exposed. We have thus shown that the ED substances most present in mass concentration are comparable for the whole population, whatever the diet considered. However, a second approach made it possible to highlight, for a given diet, the substances whose exposure is statistically higher than in the diet of the general population. Thus, significantly different ED mixtures could be established for each diet. For example, diets with a high proportion of animal-based foods induce significantly higher exposures to some persistent organic pollutants (e.g., PCDD/F, brominated flame retardants), whereas these exposures are lower for Mediterranean-type diet. On the other hand, the latter, richer in fruits and vegetables, is the one for which pesticides represent a specific signature.These results now pave the way for studying the specific effects of these cocktails of endocrine disruptors, each of which is representative of a type of chronic exposure linked to specific diets.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
CHU Lille
Institut Pasteur de Lille
CHU Lille
Institut Pasteur de Lille
Date de dépôt :
2024-05-06T21:19:51Z
2024-06-12T06:39:17Z
2024-06-12T06:39:17Z