Title :

The hypothalamic-pituitary-gonadal axis and the enigma of Alzheimer disease sex differences.

Author(s) :

Sauve, Florent [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172
Kacimi, Loïc [Auteur]
Lille Neurosciences & Cognition - U 1172 [LilNCog]
Prevot, Vincent [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172

Journal title :

Nature Reviews Endocrinology

Abbreviated title :

Nat Rev Endocrinol

Volume number :

20

Pages :

317–318

Publication date :

2024-03-22

ISSN :

1759-5037

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Alzheimer disease has a sex bias: women are twice as likely as men to be affected. Studies have linked elevated follicle-stimulating hormone (FSH) levels to worsened Alzheimer disease pathology and cognitive decline in ...
Show more >Alzheimer disease has a sex bias: women are twice as likely as men to be affected. Studies have linked elevated follicle-stimulating hormone (FSH) levels to worsened Alzheimer disease pathology and cognitive decline in mice. Exploring the interaction of FSH with APOE4 has uncovered new aspects of Alzheimer disease. The therapeutic potential of FSH and gonadotropin-releasing hormone have also been highlighted.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Lille Neurosciences & Cognition (LilNCog) - U 1172

Submission date :

2024-05-06T22:39:46Z
2024-06-03T13:43:41Z