Title :

Efficient H2O2-sonochemical treatment of Penicillin G in water: Optimization, DI-HRMS ultra-trace by-products analysis, and degradation pathways

Author(s) :

Bendjelloul, Ryma [Auteur]
Université des Sciences et de la Technologie Houari Boumediene = University of Sciences and Technology Houari Boumediene [Alger] [USTHB]
Bensmaili, Aicha [Auteur]
Université des Sciences et de la Technologie Houari Boumediene = University of Sciences and Technology Houari Boumediene [Alger] [USTHB]
Berkani, Mohammed [Auteur]
Université Salah Boubnider Constantine 3
Aminabhavi, Tejraj M. [Auteur]
KLE Technological University
Vasseghian, Yasser [Auteur]
Seoul National University [Seoul] [SNU]
Appasamy, Danen [Auteur]
University of Wolverhampton
Kadmi, Yassine [Auteur]
Laboratoire Avancé de Spectroscopie pour les Intéractions la Réactivité et l'Environnement - UMR 8516 [LASIRE]

Journal title :

Process Saf. Environ. Protect.

Abbreviated title :

Process Saf. Environ. Protect.

Volume number :

185

Pages :

-

Publication date :

2024-06-10

ISSN :

0957-5820

English keyword(s) :

Sonochemical degradation
Penicillin G
Response surface methodology
High -resolution mass spectrometry
QuEChERS extraction method

HAL domain(s) :

Chimie/Chimie théorique et/ou physique

English abstract : [en]

Due to widespread usage of antibiotics, the possibility of surface and groundwater contamination with such pollutants has significantly increased over the years as such antibiotics have been widely reported in water bodies. ...
Show more >Due to widespread usage of antibiotics, the possibility of surface and groundwater contamination with such pollutants has significantly increased over the years as such antibiotics have been widely reported in water bodies. This study reports on the elimination of toxic antibiotic Penicillin G (PG) from wastewaters sources via the sonochemical process in the presence of hydrogen peroxide (H2O2) as well as to identify the degradation by-products. The effect of initial pH, pollutant dosage and presence of hydrogen peroxide on the degradability was examined. Response Surface Methodology (RSM) was used to model the sonochemical process with high correlation of (R2= 0.9784) and predictions agreed well with the experimental results. Box-Behnken Design (BBD) and RSM equations were used to determine the optimal values of experimental conditions for the PG degradation at the optimum conditions: PG dose of 20 mgL−1, pH 3.4 and hydrogen peroxide (H2O2) concentration of 600 mgL−1. Under the optimized conditions, removal efficiency reached 97% and by-products formed during sonochemical degradation were identified via QuEChERS method (Quick, Easy, Cheap, Effective, Rugged, and Safe), while the pre-concentration by evaporation was followed by the direct infusion-high resolution mass spectrometry technique (DI-HRMS). This is the first study to report a detailed investigation on PG degradation products under the sonochemical treatment combined with QuEChERS method to DI-HRMS techniques. Such advanced methods allowed us to determine the analyte substance found in water at low concentrations (ng L−1). The seven by-products have been detected where two possible degradation pathways were proposed with a resulting total elimination of PG.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
CNRS

Collections :

• Laboratoire Avancé de Spectroscopie pour les Intéractions la Réactivité et l'Environnement (LASIRE) - UMR 8516

Research team(s) :

Physicochimie de l’Environnement (PCE)

Submission date :

2024-06-13T21:02:29Z
2024-06-26T06:59:22Z