Title :

Lipomatoses.

Author(s) :

Dupuis, Hippolyte [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Lemaitre, Madleen [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Université de Lille
Jannin, Arnaud [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Université de Lille
Cancer Heterogeneity, Plasticity and Resistance to Therapies (CANTHER) - UMR 9020 - UMR 1277
Douillard, Claire [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Stephanie, Espiard [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Université Lille Nord (France)
Vantyghem, Marie-Christine [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Université de Lille
Recherche translationnelle sur le diabète - U 1190 [RTD]

Journal title :

Ann Endocrinol (Paris)

Abbreviated title :

Ann Endocrinol (Paris)

Volume number :

85

Pages :

231-247

Publication date :

2024-06-15

ISSN :

2213-3941

Keyword(s) :

Lipomatoses
Lipomes
Maladie de Dercum
Maladie de Madelung
Launois-Bensaude
Angiolipomatose
Lipoedeme
Hibernome
Syndrome de Protée
Syndrome de Cowden
LMNA
MEN1
PIK3CA
MERFF
NF1

English keyword(s) :

Lipomatosis
Lipomas
Dercum disease
Madelung disease
Launois-Bensaude
Angiolipomatosis Lipedema
Hibernoma
Proteus and Cowden syndromes
LMNA
MEN1
PIK3CA
MERFF
NF1

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Lipomatoses are benign proliferation of adipose tissue. Lipomas (benign fat tumors) are the most common component of lipomatosis. They may be unique or multiple, encapsulated or not, subcutaneous or sometimes visceral. In ...
Show more >Lipomatoses are benign proliferation of adipose tissue. Lipomas (benign fat tumors) are the most common component of lipomatosis. They may be unique or multiple, encapsulated or not, subcutaneous or sometimes visceral. In some cases, they form large areas of non-encapsulated fat hypertrophy, with a variable degree of fibrosis. They can develop despite the absence of obesity. They may be familial or acquired. At difference with lipodystrophy syndromes, they are not associated with lipoatrophy areas, except in some rare cases such as type 2 familial partial lipodystrophy syndromes (FPLD2). Their metabolic impact is variable in part depending on associated obesity. They may have functional or aesthetic consequences. Lipomatosis may be isolated, be part of a syndrome, or may be visceral. Isolated lipomatoses include multiple symmetrical lipomatosis (Madelung disease or Launois-Bensaude syndrome), familial multiple lipomatosis, the painful Dercum's disease also called Adiposis Dolorosa or Ander syndrome, mesosomatic lipomatosis also called Roch-Leri lipomatosis, familial angiolipomatosis, lipedema and hibernomas. Syndromic lipomatoses include PIK3CA-related disorders, Cowden/PTEN hamartomas-tumor syndrome, some lipodystrophy syndromes, and mitochondrial diseases, especially MERRF, multiple endocrine neoplasia type 1, neurofibromatosis type 1, Wilson disease, Pai or Haberland syndromes. Finally, visceral lipomatoses have been reported in numerous organs and sites: pancreatic, adrenal, abdominal, epidural, mediastinal, epicardial… The aim of this review is to present the main types of lipomatosis and their physiopathological component, when it is known.Show less >

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Recherche translationnelle sur le diabète (RTD) - U1190

Submission date :

2024-06-26T21:31:26Z
2024-07-05T09:31:45Z