Metallic ion release after knee prosthesis implantation: a prospective study

Lons, Adrien; Putman, Sophie; pasquier, gilles; Migaud, Henri; Drumez, Elodie; Girard, Julien

Type de document :

Article dans une revue scientifique

DOI :

10.1007/s00264-017-3528-9

PMID :

28616704

URL permanente :

http://hdl.handle.net/20.500.12210/12083

Titre :

Metallic ion release after knee prosthesis implantation: a prospective study

Auteur(s) :

Lons, Adrien [Auteur]
Putman, Sophie [Auteur]

Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
pasquier, gilles [Auteur]

Marrow Adiposity & Bone Lab - Adiposité Médullaire et Os - ULR 4490 [MABLab]
Migaud, Henri [Auteur]

Marrow Adiposity & Bone Lab - Adiposité Médullaire et Os - ULR 4490 [MABLab]
Drumez, Elodie [Auteur]

Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Girard, Julien [Auteur]

Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 [URePSSS]

Titre de la revue :

International orthopaedics

Nom court de la revue :

Int. Orthop.

Numéro :

Pagination :

2503-2508

Date de publication :

2017-12-01

ISSN :

0341-2695

Mot(s)-clé(s) en anglais :

Metallic ions
Chromium
Cobalt
Titanium
Knee prosthesis

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Metal-on-metal (MoM) hip replacement bearings produce metallic ions that can cause health complications. Metallic release also occurs with other materials, but data on metallic ion levels after knee arthroplasty are sparse. ...
Lire la suite >Metal-on-metal (MoM) hip replacement bearings produce metallic ions that can cause health complications. Metallic release also occurs with other materials, but data on metallic ion levels after knee arthroplasty are sparse. We postulate that knee replacement generates elevating metallic ions (chromium (Cr), cobalt (Co) and titanium (Ti)) during the first year after implantation. This ongoing prospective study included all patients who underwent the same type of knee arthroplasty between May and December 2013. Cr, Co and Ti levels were measured in whole blood at pre-operation and one-year follow-up (6 and 12 months). Clinical and radiographic data (range of motion, Oxford, International Knee Society (IKS) and satisfaction scores) were recorded. In 90 patients, preoperative Cr, Co and Ti metallic ion levels were respectively 0.45 μg/l, 0.22 μg/l, 2.94 μg/l and increased to 1.27 μg/l, 1.41 μg/l, 4.08 μg/l (p < 0.0001) at last one-year follow-up. Mean Oxford and IKS scores rose, respectively, from 45.9 (30-58) and 24.9 (12-52) to 88.3 (0-168) and 160.8 (93-200) (p < 0.001). After the implantation of knee arthroplasty, we found significant blood elevation of Cr, Co and Ti levels one year after implantation exceeding the normal values. This metallic ion release could lead to numerous effects: allergy, hypersensitivity, etc.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
Univ. Littoral Côte d’Opale
Univ. Artois
Université de Lille

Collections :

Équipe(s) de recherche :

Activité Physique, Muscle, Santé (APMS)

Date de dépôt :

2019-09-24T07:29:02Z
2021-05-17T07:19:12Z

Numéro de version	Lien	Date de modification
2	20.500.12210/12083*	2021-05-17T07:18:19Z
1	20.500.12210/12083.1	2019-09-24T07:29:02Z

Metallic ion release after knee prosthesis ...

BibTeX

CSV

Excel

RIS

Historique des modifications

Metallic ion release after knee prosthesis ... BibTeX CSV Excel RIS

Historique des modifications

Metallic ion release after knee prosthesis ...

BibTeX

CSV

Excel

RIS