Prevalence of Eosinophilic Esophagitis in ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Prevalence of Eosinophilic Esophagitis in Adolescents with Esophageal Atresia.
Auteur(s) :
Lardenois, Emilie [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Michaud, Laurent [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Schneider, Anne [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Onea, Mihaela [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Rebeuh, Julie [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Renaud, Florence [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
gottrand, Fréderic [Auteur]
Lille Inflammation Research International Center (LIRIC) - U995
Lille Inflammation Research International Center - U 995 [LIRIC]
Leteurtre, Emmanuelle [Auteur]
Cancer Heterogeneity, Plasticity and Resistance to Therapies (CANTHER) - UMR 9020 - UMR 1277
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Michaud, Laurent [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Schneider, Anne [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Onea, Mihaela [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Rebeuh, Julie [Auteur]
Centre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
Renaud, Florence [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
gottrand, Fréderic [Auteur]
Lille Inflammation Research International Center (LIRIC) - U995
Lille Inflammation Research International Center - U 995 [LIRIC]
Leteurtre, Emmanuelle [Auteur]
Cancer Heterogeneity, Plasticity and Resistance to Therapies (CANTHER) - UMR 9020 - UMR 1277
Titre de la revue :
Journal of pediatric gastroenterology and nutrition
Nom court de la revue :
J. Pediatr. Gastroenterol. Nutr.
Numéro :
69
Pagination :
52-56
Éditeur :
Wolters Kluwer
Date de publication :
2019-01-02
ISSN :
1536-4801
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
OBJECTIVE: Eosinophilic esophagitis (EoE) is an increasingly recognized childhood disease. Esophageal atresia (EA) is the most frequent congenital malformation of the esophagus. Recently, cases of EoE occurring in patients ...
Lire la suite >OBJECTIVE: Eosinophilic esophagitis (EoE) is an increasingly recognized childhood disease. Esophageal atresia (EA) is the most frequent congenital malformation of the esophagus. Recently, cases of EoE occurring in patients with EA have been reported, although the exact prevalence of EoE in EA remains unknown. The aim is to investigate the prevalence of EoE among EA in adolescents and to describe these patients' characteristics. METHODS: Systematic upper gastrointestinal endoscopies with multistage esophageal biopsies were prospectively performed in 63 adolescents with EA. A standardized form was used to collect clinical and endoscopic data. Diagnosis of EoE was made as ≥15 intraepithelial eosinophils/high power field, whatever the response on proton pump inhibitors therapy. RESULTS: Six patients (9.5%) presented an EoE (17-100 eosinophils/high power field). An atopic condition was reported more frequently in the eosinophil ≥15 group than in patients with no EoE (66% vs 16%; P = 0.014). Except for chest pain, symptoms and endoscopic features were similar in patients with EoE and patients with no EoE. CONCLUSIONS: In our series of 63 patients born with EA, mainly distal tracheoesophageal fistula, the prevalence of EoE is increased, and therefore should be considered in adolescents with EA.Lire moins >
Lire la suite >OBJECTIVE: Eosinophilic esophagitis (EoE) is an increasingly recognized childhood disease. Esophageal atresia (EA) is the most frequent congenital malformation of the esophagus. Recently, cases of EoE occurring in patients with EA have been reported, although the exact prevalence of EoE in EA remains unknown. The aim is to investigate the prevalence of EoE among EA in adolescents and to describe these patients' characteristics. METHODS: Systematic upper gastrointestinal endoscopies with multistage esophageal biopsies were prospectively performed in 63 adolescents with EA. A standardized form was used to collect clinical and endoscopic data. Diagnosis of EoE was made as ≥15 intraepithelial eosinophils/high power field, whatever the response on proton pump inhibitors therapy. RESULTS: Six patients (9.5%) presented an EoE (17-100 eosinophils/high power field). An atopic condition was reported more frequently in the eosinophil ≥15 group than in patients with no EoE (66% vs 16%; P = 0.014). Except for chest pain, symptoms and endoscopic features were similar in patients with EoE and patients with no EoE. CONCLUSIONS: In our series of 63 patients born with EA, mainly distal tracheoesophageal fistula, the prevalence of EoE is increased, and therefore should be considered in adolescents with EA.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
CHU Lille
Inserm
Université de Lille
Inserm
Université de Lille
Collections :
Date de dépôt :
2019-10-22T08:09:15Z
2021-06-15T12:10:30Z
2023-03-22T08:09:30Z
2021-06-15T12:10:30Z
2023-03-22T08:09:30Z
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