[iron and neurodevelopment]

Vallee, Louis

Document type :

Article dans une revue scientifique: Article original

DOI :

10.1016/S0929-693X(17)24005-6

PMID :

28622777

Permalink :

http://hdl.handle.net/20.500.12210/15801

Title :

[iron and neurodevelopment]

Author(s) :

Vallee, Louis [Auteur]

Journal title :

Archives de pediatrie . organe officiel de la Societe francaise de pediatrie

Abbreviated title :

Arch Pediatr

Volume number :

Pages :

5S18-5S22

Publication date :

2017-05-01

ISSN :

1769-664X

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

In the central nervous system, iron is a cofactor of many metabolic processes and synthesis of aminergic neurotransmitters. Iron plays an major function on brain development from the prenatal period to teenage years. The ...
Show more >In the central nervous system, iron is a cofactor of many metabolic processes and synthesis of aminergic neurotransmitters. Iron plays an major function on brain development from the prenatal period to teenage years. The blood-brain barrier modulates concentration of iron in the brain. In case of iron deficiency in the child, the negative impact on the myelinogenesis and synaptogenesis are well proven, with negative effects on psychomotor and cognitive functions. Iron supplementation has a beneficial effect, even if there is no anemia. The consequences of iron deficiency are more harmful as deficiency is early. The main mechanisms involved about iron and brain are reviewed.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
CNRS
Inserm
Université de Lille

Collections :

Lille Neurosciences & Cognition (LilNCog) - U 1172

Research team(s) :

Troubles cognitifs dégénératifs et vasculaires

Submission date :

2019-11-27T13:01:30Z

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