Role of cerebral microbleeds for intracerebral haemorrhage and dementia

Moulin, Solene; Cordonnier, Charlotte

Type de document :

Article dans une revue scientifique: Article de synthèse/Review paper

DOI :

10.1007/s11910-019-0969-0

PMID :

31218453

URL permanente :

http://hdl.handle.net/20.500.12210/15842

Titre :

Role of cerebral microbleeds for intracerebral haemorrhage and dementia

Auteur(s) :

Moulin, Solene [Auteur]
Cordonnier, Charlotte [Auteur]

Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]

Titre de la revue :

Current Neurology and Neuroscience Reports

Nom court de la revue :

Curr Neurol Neurosci Rep

Numéro :

Pagination :

Date de publication :

2019-06-19

ISSN :

1534-6293

Mot(s)-clé(s) en anglais :

Ischaemic stroke
Cerebral microbleeds
Cognitive impairment
Dementia
Intracerebral haemorrhage

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

OBJECTIVE: Cerebral microbleeds (CMB)-small round or ovoid lesions detected in hyposignal on blood-sensitive MRI sequences-are promising radiological biomarkers of cerebral small vessel disease. Their relations with ischaemic ...
Lire la suite >OBJECTIVE: Cerebral microbleeds (CMB)-small round or ovoid lesions detected in hyposignal on blood-sensitive MRI sequences-are promising radiological biomarkers of cerebral small vessel disease. Their relations with ischaemic or haemorragic stroke and their potential contribution to dementia have been extensively addressed. This article reviews recent research on the clinical significance of CMB that remains to be determined. RESULTS: The presence, burden and location of CMB allow to obtain a more accurate estimate of intracerebral haemorrhage and ischaemic stroke risk. Most studies evaluating the association between CMB and dementia are hampered by methodological limitations and show conflicting results. CMB mainly reflect the severity of the underlying small vessel disease and should not be interpreted independently of the others neuroimaging biomarkers or the clinical setting. Future large prospective longitudinal studies and randomized controlled trials in various settings are required to determine whether specific therapies are beneficial in case of incidental findings.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
CNRS
Inserm
Université de Lille

Collections :

Lille Neurosciences & Cognition (LilNCog) - U 1172

Équipe(s) de recherche :

Troubles cognitifs dégénératifs et vasculaires

Date de dépôt :

2019-11-27T13:01:42Z

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