Title :

The impact of discontinuing methylphenidate on weight and eating behavior

Author(s) :

Bénard, Victoire [Auteur]
Service de Psychiatrie [CHRU Lille]
Cottencin, Olivier [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Guardia, Dewi [Auteur]
Vaiva, Guillaume [Auteur]
Service de Psychiatrie [CHRU Lille]
Rolland, Benjamin [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]

Journal title :

The International Journal of Eating Disorders

Abbreviated title :

Int. J. Eating Disord.

Volume number :

48

Pages :

345-348

Publication date :

2014-04-22

ISSN :

0276-3478

English keyword(s) :

drug toxicity
weight gain
amphetamines
pharmacovigilance
eating disorders
methylphenidate
attention deficit disorder with hyperactivity
Humans
Central Nervous System Stimulants/therapeutic use*
Adolescent
Attention Deficit Disorder with Hyperactivity/drug therapy*
Body Mass Index
Feeding Behavior/drug effects*
Weight Gain/drug effects*
Recurrence
Methylphenidate/therapeutic use*
Male

HAL domain(s) :

Sciences du Vivant [q-bio]
Sciences cognitives

English abstract : [en]

Chronic administration of the amphetamine-derivative methylphenidate (MPH) may induce appetite reduction and weight loss. By contrast, the effects that stopping chronic MPH may exert on eating behavior and body weight are ...
Show more >Chronic administration of the amphetamine-derivative methylphenidate (MPH) may induce appetite reduction and weight loss. By contrast, the effects that stopping chronic MPH may exert on eating behavior and body weight are poorly known. We report the case of a male patient with childhood attention deficit/hyperactivity disorder (ADHD), who discontinued MPH treatment at the age of 11 years and was lost to follow-up until the age of 16. The patient's body mass index increased by five points within 1 year of MPH cessation while the symptoms of ADHD were re-emerging. The patient secondarily developed DSM-5 criteria for eating disorders. Discontinuing chronic MPH can significantly affect weight and eating behavior. Such risks should warrant further studies, as they could be particularly increased in patients with ADHD, who share common vulnerability factors with both obesity and eating disorders.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
CNRS
Inserm
Université de Lille

Collections :

• Lille Neurosciences & Cognition (LilNCog) - U 1172

Research team(s) :

Troubles cognitifs dégénératifs et vasculaires

Submission date :

2019-11-27T13:02:35Z
2020-02-04T16:39:44Z
2020-03-17T13:02:12Z
2020-04-09T12:39:32Z
2020-04-09T12:42:15Z