Title :

Real-time light dosimetry for intra-cavity photodynamic therapy: application for pleural mesothelioma treatment

Author(s) :

Betrouni, Nacim [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U1171
Munck, Camille [Auteur]
Bensoltana, Wael [Auteur]
Baert, Gregory [Auteur]
Thérapies Lasers Assistées par l'Image pour l'Oncologie (ONCO-THAI) - U1189
Dewalle-Vignion, Anne-Sophie [Auteur]
SCHERPEREEL, Arnaud [Auteur]
Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 8204
Mordon, Serge [Auteur]
Thérapies Lasers Assistées par l'Image pour l'Oncologie (ONCO-THAI) - U1189

Journal title :

Photodiagnosis and photodynamic therapy

Abbreviated title :

Photodiagnosis Photodyn. Ther.

Volume number :

18

Pages :

155-161

Publication date :

2017-06-01

ISSN :

1572-1000

English keyword(s) :

Dosimetry
Light distribution modeling
Intra-cavity application
Photodynamic therapy
Imaging
Real time tracking
Mesh:Mesothelioma/pathology
Mesh:Mesothelioma/drug therapy*
Mesh:Light
Mesh:Treatment Outcome
Mesh:Humans
Mesh:Radiotherapy Dosage
Mesh:Radiometry/methods*
Mesh:Feasibility Studies
Mesh:Dose-Response Relationship
Mesh:Radiation
Mesh:Dose-Response Relationship
Mesh:Drug
Mesh:Computer Systems
Mesh:Pleural Neoplasms/pathology
Mesh:Pleural Neoplasms/drug therapy*
Mesh:Photosensitizing Agents/administration & dosage*
Mesh:Photometry/methods*
Mesh:Photochemotherapy/methods*
Mesh:Phantoms
Mesh:Imaging

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Complete and homogeneous illumination of the target is necessary for the success of a photodynamic therapy (PDT) procedure. In most applications, light dosimetry is done using detectors placed at strategic locations of the ...
Show more >Complete and homogeneous illumination of the target is necessary for the success of a photodynamic therapy (PDT) procedure. In most applications, light dosimetry is done using detectors placed at strategic locations of the target. In this study we propose a novel approach based on the combination of light distribution modeling with spatial localization of the light applicator for real time estimation and display of the applied dose on medical images. The feasibility approach is demonstrated for intrapleural PDT of malignant pleural mesothelioma.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
CNRS
Inserm
Institut Pasteur de Lille
Université de Lille

Collections :

• Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 8204
• Thérapies Lasers Assistées par l'Image pour l'Oncologie (ONCO-THAI) - U1189
• Troubles cognitifs dégénératifs et vasculaires - U1171

Submission date :

2019-11-27T13:05:18Z