Titre :

Characterization and prediction of theory of mind disorders in temporal lobe epilepsy

Auteur(s) :

Hennion, Sophie [Auteur]
Service de neurophysiologie clinique [CHRU Lille]
Delbeuck, Xavier [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Duhamel, Alain [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Lopes, Renaud [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Semah, Franck [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Tyvaert, Louise [Auteur]
Service de neurophysiologie clinique [CHRU Lille]
Derambure, Philippe [Auteur]
Médicaments et Molécules pour agir sur les Systèmes Vivants (M2SV) - U1177
Médicaments et molécules pour les systèmes vivants - U 1177 [M2SV]
Szurhaj, William [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]

Titre de la revue :

Neuropsychology

Nom court de la revue :

Neuropsychology

Numéro :

29

Pagination :

485-492

Date de publication :

2015-05-01

ISSN :

0894-4105

Mot(s)-clé(s) en anglais :

temporal lobe epilepsy
theory of mind
empathy
anhedonia
affective states

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

OBJECTIVE: Patients with temporal lobe epilepsy (TLE) have impaired theory of mind (ToM). However, ToM involves a variety of processes, such as understanding a person's intentions ("cognitive" ToM) and emotional states ...
Lire la suite >OBJECTIVE: Patients with temporal lobe epilepsy (TLE) have impaired theory of mind (ToM). However, ToM involves a variety of processes, such as understanding a person's intentions ("cognitive" ToM) and emotional states ("affective" ToM). The objectives of the present study were to characterize ToM disorders in TLE patients, identify patients at risk of ToM disorders, and study the relationships between psychobehavioral and quality of life factors and ToM disorders. METHODS: Fifty TLE patients and 50 controls performed ToM tasks assessing their understanding of verbal clumsiness (faux pas), sarcastic remarks, and mentalistic actions. Demographic, cognitive, and psychobehavioral data, and (for TLE patients) clinical and quality of life factors, were recorded. RESULTS: Compared with controls, TLE patients showed impairments in all ToM tasks: 84% misunderstood faux pas, and around 50% misunderstood sarcasm. A long duration of epilepsy and young age at onset were risk factors for ToM impairments. In TLE patients, ToM impairments were associated with impaired empathy and anhedonia. Their affective states were less positively and more negatively valenced than in controls. Low positive affectivity was predictive of greater cognitive and affective ToM impairments for the faux pas task, and high negative affectivity was predictive of greater cognitive ToM abilities for the sarcasm task. The lack of social support was correlated with impaired ToM but was not a predictive factor. CONCLUSIONS: Both cognitive and affective ToM processes are impaired in TLE patients. Impaired ToM has an impact on empathy abilities and is related to affective disturbances in TLE patients.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
CNRS
Inserm
Université de Lille

Collections :

• Médicaments et Molécules pour agir sur les Systèmes Vivants (M2SV) - U1177
• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Date de dépôt :

2019-11-27T13:33:40Z
2021-12-15T09:53:02Z