Title :

Whole-brain high-resolution structural connectome: inter-subject validation and application to the anatomical segmentation of the striatum

Author(s) :

Besson, Pierre [Auteur]
Carriere, Nicolas [Auteur]
Bandt, S Kathleen [Auteur]
Tommasi, Marc [Auteur]
Centre de Recherche en Informatique, Signal et Automatique de Lille (CRIStAL) - UMR 9189
Centre de Recherche en Informatique, Signal et Automatique de Lille - UMR 9189 [CRIStAL]
Leclerc, Xavier [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Derambure, Philippe [Auteur]
Médicaments et Molécules pour agir sur les Systèmes Vivants (M2SV) - U1177
Médicaments et molécules pour les systèmes vivants - U 1177 [M2SV]
Médicaments et molécules pour les systèmes vivants - U 1177 [M2SV]
Lopes, Renaud [Auteur]
Tyvaert, Louise [Auteur]

Journal title :

Brain topography

Abbreviated title :

Brain Topogr.

Volume number :

30

Pages :

291-302

Publication date :

2017-05-01

ISSN :

0896-0267

English keyword(s) :

High-resolution
Connectome
Diffusion magnetic resonance imaging
Surface-based connectivity
Striatum clustering

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

The present study describes extraction of high-resolution structural connectome (HRSC) in 99 healthy subjects, acquired and made available by the Human Connectome Project. Single subject connectomes were then registered ...
Show more >The present study describes extraction of high-resolution structural connectome (HRSC) in 99 healthy subjects, acquired and made available by the Human Connectome Project. Single subject connectomes were then registered to the common surface space to allow assessment of inter-individual reproducibility of this novel technique using a leave-one-out approach. The anatomic relevance of the surface-based connectome was examined via a clustering algorithm, which identified anatomic subdivisions within the striatum. The connectivity of these striatal subdivisions were then mapped on the cortical and other subcortical surfaces. Findings demonstrate that HRSC analysis is robust across individuals and accurately models the actual underlying brain networks related to the striatum. This suggests that this method has the potential to model and characterize the healthy whole-brain structural network at high anatomic resolution.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
CNRS
Centrale Lille
Inserm
Université de Lille

Collections :

• Médicaments et Molécules pour agir sur les Systèmes Vivants (M2SV) - U1177

Submission date :

2019-11-27T13:34:02Z