Title :

Qualitative and quantitative assessment of self-reported cognitive difficulties in nondemented elders: association with medical help seeking, cognitive deficits, and ?-amyloid imaging

Author(s) :

La Joie, Renaud [Auteur]
Perrotin, Audrey [Auteur]
Egret, Stéphanie [Auteur]
Pasquier, Florence [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U1171
Tomadesso, Clemence [Auteur]
Mezenge, Florence [Auteur]
Desgranges, Beatrice [Auteur]
De La Sayette, Vincent [Auteur]
Chetelat, Gael [Auteur]

Journal title :

Alzheimer's & dementia (Amsterdam, Netherlands)

Abbreviated title :

Alzheimers Dement (Amst)

Volume number :

5

Pages :

23-34

Publication date :

2016-01-01

ISSN :

2352-8729

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

BACKGROUND: Subjective cognitive decline (SCD) could help identify early stages of Alzheimer's disease. However, SCD is multidetermined and protean, and the type of cognitive complaint associated with preclinical Alzheimer's ...
Show more >BACKGROUND: Subjective cognitive decline (SCD) could help identify early stages of Alzheimer's disease. However, SCD is multidetermined and protean, and the type of cognitive complaint associated with preclinical Alzheimer's disease needs refinement. METHODS: A total of 185 nondemented elders recruited from either the community or from a memory clinic filled a questionnaire. We searched for item responses associated with medical help seeking, cognitive deficits, and β-amyloidosis. RESULTS: Compared with community-recruited control subjects (nnn CONCLUSIONS: Detailed evaluation of SCD could provide accessible indication of the presence of β-amyloid or cognitive deficits, which might prove useful for early diagnosis and clinical trial enrichment strategies.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
CNRS
Inserm
Université de Lille

Collections :

• Troubles cognitifs dégénératifs et vasculaires - U1171

Submission date :

2019-11-27T13:34:35Z