Title :

Factors associated with alzheimer''s disease: an overview of reviews

Author(s) :

Rochoy, Michael [Auteur]
Troubles cognitifs vasculaires et dégénératifs
Rivas, V. [Auteur]
Chazard, Emmanuel [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Decarpentry, E. [Auteur]
Saudemont, G. [Auteur]
Hazard, P-A [Auteur]
Puisieux, Francois [Auteur]
221576|||Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS] (VALID)
Gautier, Sophie [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U1171
Bordet, Regis [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U1171

Journal title :

The Journal of prevention of Alzheimer's disease

Abbreviated title :

J Prev Alzheimers Dis

Volume number :

6

Pages :

121-134

Publisher :

Springer Link

Publication date :

2019-01-01

ISSN :

2426-0266

English keyword(s) :

risk factors
Alzheimer''s disease
early intervention
prevention

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Alzheimer's disease (AD) is a frequent pathology, with a poor prognosis, for which no curative treatment is available in 2018. AD prevention is an important issue, and is an important research topic. In this manuscript, ...
Show more >Alzheimer's disease (AD) is a frequent pathology, with a poor prognosis, for which no curative treatment is available in 2018. AD prevention is an important issue, and is an important research topic. In this manuscript, we have synthesized the literature reviews and meta-analyses relating to modifiable risk factors associated with AD. Smoking, diabetes, high blood pressure, obesity, hypercholesterolemia, physical inactivity, depression, head trauma, heart failure, bleeding and ischemic strokes, sleep apnea syndrome appeared to be associated with an increased risk of AD. In addition to these well-known associations, we highlight here the existence of associated factors less described: hyperhomocysteinemia, hearing loss, essential tremor, occupational exposure to magnetic fields. On the contrary, some oral antidiabetic drugs, education and intellectual activity, a Mediterranean-type diet or using Healthy Diet Indicator, consumption of unsaturated fatty acids seemed to have a protective effect. Better knowledge of risk factors for AD allows for better identification of patients at risk. This may contribute to the emergence of prevention policies to delay or prevent the onset of AD.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
CNRS
Inserm
Université de Lille

Collections :

• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Submission date :

2019-11-27T13:35:16Z
2024-03-27T09:09:03Z